Results 31 to 40 of about 460,994 (251)
MAP3K Family Review and Correlations with Patient Survival Outcomes in Various Cancer Types
Frontiers in Bioscience-Landmark, 2022 The mitogen-activated protein kinase (MAPK) pathways are ubiquitous in cellular signaling and are essential for proper biological functions. Disruptions in this signaling axis can lead to diseases such as the development of cancer.
Khoa Nguyen +11 more
doaj +1 more source
Bridelia ferruginea Produces Anti-neuroinflammatory Activity through Inhibition of Nuclear Factor-kappa B and p38 MAPK Signalling [PDF]
, 2012 Bridelia ferruginea is commonly used in traditional African medicine (TAM) for treating various inflammatory conditions. Extracts from the plant have been shown to exhibit anti-inflammatory property in a number of in vivo models.
Aderogba, Mutallib A. +7 more
core +1 more source
MAPK phosphatase-1 represents a novel antiinflammatory target of glucocorticoids in the human endothelium [PDF]
, 2007 Glucocorticoids are well-established anti- inflammatory drugs thought to mainly act by inhibition of proinflammatory transcription factors like NF-κB.
Timm Schroeder +20 more
core +1 more source
Diverse physiological functions for dual-specificity MAP kinase phosphatases [PDF]
, 2006 A structurally distinct subfamily of ten dual-specificity (Thr/Tyr) protein phosphatases is responsible for the regulated dephosphorylation and inactivation of mitogen-activated protein kinase (MAPK) family members in mammals.
Keyse, Stephen M, Dickinson, Robin J
core +1 more source
PSMA redirects MAPK to PI3K-AKT signaling to promote prostate cancer progression
Molecular & Cellular Oncology, 2017 Increased Prostate Specific Membrane Antigen expression promotes tumor progression in prostate epithelium by dysregulating the β1-integrin/type I insulin-like growth factor receptor axis, resulting in a shift in signaling from the less aggressive mitogen-
Leslie Ann Caromile, Linda H. Shapiro
doaj +1 more source
Pharmaceutical Biology, 2017 Context: Punica granatum L (Punicaceae) flower is an important diabetes treatment in oriental herbal medicine. Objective: This study investigates the inflammation effects of pomegranate flower (PFE) ethanol extract in LPS-induced RAW264.7 cells ...
Jianjun Xu +2 more
doaj +1 more source
Cell Stress, 2020 The widespread application of immune-checkpoint blockade (ICB) has resulted in unprecedented response rates in patients with immunogenic cancers, such as melanoma and lung cancer.
Daniel Baumann, Rienk Offringa
doaj +1 more source
, 2020 The evolution of insect resistance to pesticides poses a continuing threat to agriculture and human health. While much is known about the proximate molecular and biochemical mechanisms that confer resistance far less is known about the regulation of ...
Z Guo (9852683) +17 more
core +5 more sources
Alhiwar: Jurnal Ilmu dan Teknik DakwahChildren with special needs also have the right to develop mental and spiritual aspects so that they develop optimally according to their circumstances.
Rahmiyati Rahmiyati, Hapiz Al Ansyari
doaj +1 more source
p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice [PDF]
, 2018 Muscle wasting is the key manifestation of cancer-associated cachexia, a lethal metabolic disorder seen in over 50% of cancer patients. Autophagy is activated in cachectic muscle of cancer hosts along with the ubiquitin-proteasome pathway (UPP ...
HoangAnh Amy Doan +9 more
core +1 more source