Results 21 to 30 of about 360,097 (261)
MAP3K Family Review and Correlations with Patient Survival Outcomes in Various Cancer Types
Frontiers in Bioscience-Landmark, 2022 The mitogen-activated protein kinase (MAPK) pathways are ubiquitous in cellular signaling and are essential for proper biological functions. Disruptions in this signaling axis can lead to diseases such as the development of cancer.
Khoa Nguyen +11 more
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PSMA redirects MAPK to PI3K-AKT signaling to promote prostate cancer progression
Molecular & Cellular Oncology, 2017 Increased Prostate Specific Membrane Antigen expression promotes tumor progression in prostate epithelium by dysregulating the β1-integrin/type I insulin-like growth factor receptor axis, resulting in a shift in signaling from the less aggressive mitogen-
Leslie Ann Caromile, Linda H. Shapiro
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Pharmaceutical Biology, 2017 Context: Punica granatum L (Punicaceae) flower is an important diabetes treatment in oriental herbal medicine. Objective: This study investigates the inflammation effects of pomegranate flower (PFE) ethanol extract in LPS-induced RAW264.7 cells ...
Jianjun Xu +2 more
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Cell Stress, 2020 The widespread application of immune-checkpoint blockade (ICB) has resulted in unprecedented response rates in patients with immunogenic cancers, such as melanoma and lung cancer.
Daniel Baumann, Rienk Offringa
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Alhiwar: Jurnal Ilmu dan Teknik DakwahChildren with special needs also have the right to develop mental and spiritual aspects so that they develop optimally according to their circumstances.
Rahmiyati Rahmiyati, Hapiz Al Ansyari
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Translational Neuroscience, 2022 Mitogen-activated protein kinase (MAPK) pathway is a major mechanism of acute brain damage in ischemic stroke. Pre-ischemic exercise is an effective method to reduce ischemic injury.
Gao Zhen-Kun +5 more
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Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases [PDF]
Microbiology and Molecular Biology Reviews, 2011 SUMMARYThe mitogen-activated protein kinases (MAPKs) regulate diverse cellular programs by relaying extracellular signals to intracellular responses. In mammals, there are more than a dozen MAPK enzymes that coordinately regulate cell proliferation, differentiation, motility, and survival.
Marie, Cargnello, Philippe P, Roux
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Clinical and Experimental Hypertension, 2021 Objective: Hypertension is associated with a low-grade systemic inflammation in cardiovascular system. Macrophage infiltration may initiate an inflammatory process that contributes to vascular and ventricular remodeling in hypertensive human and mice ...
Yuantong Tian +5 more
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Regulation of MAPK signaling and cell death by MAPK phosphatase MKP2 [PDF]
Plant Signaling & Behavior, 2010 Mitogen-activated protein kinase (MAPK) pathways play crucial roles in developmental and adaptive responses. Depending on the stimulus, MAPK activation regulates a wide variety of plant cell responses, such as proliferation, differentiation and cell death, which normally require precise spatial and temporal control.
Vilela, Belmiro +2 more
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Involvement of the ERK MAPK Cascade in the Formation of Adhesions in the Abdominal Cavity
Acta Biomedica Scientifica, 2021 Background. ERK1 and ERK2 (extracellular signal-regulated kinase) are related protein serine / threonine kinases that are involved in the regulation of the cell cycle, cell migration and survival, differentiation, metabolism, and proliferation ...
I. A. Shurygina +4 more
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