Results 41 to 50 of about 495,928 (201)

Involvement of the ERK MAPK Cascade in the Formation of Adhesions in the Abdominal Cavity

open access: yesActa Biomedica Scientifica, 2021
Background. ERK1 and ERK2 (extracellular signal-regulated kinase) are related protein serine / threonine kinases that are involved in the regulation of the cell cycle, cell migration and survival, differentiation, metabolism, and proliferation ...
I. A. Shurygina   +4 more
doaj   +1 more source

Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway

open access: yesDrug Design, Development and Therapy, 2021
Leyi Ma,1,* Fan Wu,1,* Qingqing Shao,1 Guang Chen,2 Lijun Xu,1 Fuer Lu1 1Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 ...
Ma L, Wu F, Shao Q, Chen G, Xu L, Lu F
doaj  

A novel polysaccharide from plant fermentation extracts and its immunomodulatory activity in macrophage RAW264.7 cells

open access: yesFood and Agricultural Immunology, 2021
Plant fermentation extracts (PFEs) produced from fermenting various fruits and vegetables by microorganisms have traditionally been consumed as healthy beverages in Asia.
Yan Liang   +8 more
doaj   +1 more source

Evaluation of the GhMAPK gene expression level under salt stress in cotton cultivars

open access: yesБиотехнология и селекция растений, 2023
Background: Abiotic environmental stress factors such as salt stress, drought, oxidative stress adversely affect the development and productivity of plants.
S. A. Alizade
doaj   +1 more source

The Function of MAPK Cascades in Response to Various Stresses in Horticultural Plants

open access: yesFrontiers in Plant Science, 2020
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved signaling transduction module that transduces extracellular stimuli into intracellular responses in plants. Early studies of plant MAPKs focused on their functions in model plants.
Xiaowen He   +4 more
semanticscholar   +1 more source

Regulation of MAPK signaling and cell death by MAPK phosphatase MKP2 [PDF]

open access: yesPlant Signaling & Behavior, 2010
Mitogen-activated protein kinase (MAPK) pathways play crucial roles in developmental and adaptive responses. Depending on the stimulus, MAPK activation regulates a wide variety of plant cell responses, such as proliferation, differentiation and cell death, which normally require precise spatial and temporal control.
Vilela, Belmiro   +2 more
openaire   +3 more sources

Aloe Extracts Inhibit Skin Inflammatory Responses by Regulating NF-κB, ERK, and JNK Signaling Pathways in an LPS-Induced RAW264.7 Macrophages Model

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Fei Wang,1– 3,* Jitao Liu,1– 3 Quan An,1– 4,* Yiming Wang,1– 3 Yang Yang,1– 3 Tong Huo,1– 3 Simin Yang,5 Ruijun Ju,5 Qianghua Quan1– 4 1Research and Development Department, Yunnan Baiyao Group Health Products Co., Ltd., Kunming, People’s Republic
Wang F   +8 more
doaj  

Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update.

open access: yesPhysiological Reviews, 2012
The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs) were first elucidated in 1994, and by 2001, substantial progress had been made in identifying the architecture of the pathways upstream of these kinases as well as in ...
J. Kyriakis, J. Avruch
semanticscholar   +1 more source

Nuclear Signaling of Plant MAPKs [PDF]

open access: yesFrontiers in Plant Science, 2018
Mitogen-activated protein kinases (MAPKs) are conserved protein kinases in eukaryotes that establish signaling modules where MAPK kinase kinases (MAPKKKs) activate MAPK kinases (MAPKKs) which in turn activate MAPKs. In plants, they are involved in the signaling of multiple environmental stresses and developmental programs.
Jean Bigeard   +2 more
openaire   +5 more sources

Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy

open access: yesActa Pharmaceutica Sinica B, 2018
The mitogen-activated protein kinases (MAPK) pathway, often known as the RAS-RAF-MEK-ERK signal cascade, functions to transmit upstream signals to its downstream effectors to regulate physiological process such as cell proliferation, differentiation ...
Feifei Liu   +3 more
semanticscholar   +1 more source

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