Results 11 to 20 of about 254,157 (265)
Animal Cells and Systems, 2020 Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this ...
Zobia Umair +9 more
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Zhongliu Fangzhi Yanjiu, 2020 Objective To investigate the expression and significance of GPNMB, ERK, MMP3 and MMP9 in primary lesion and bone metastasis of renal cell carcinoma, and to analyze their correlation.
ZHAI Jianpo +4 more
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Diabetes, 2014 Increasing energy expenditure is an attractive approach to fighting the worldwide epidemic in obesity and type 2 diabetes. Exercise is an important component of good health and represents the first line of therapy for humans with a variety of metabolic disorders: obesity, diabetes, and nonalcoholic hepatic steatosis. Recent data has shown that exercise,
Wu, Jun, Spiegelman, Bruce
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Radiology and Oncology, 2019 Endometrial adenocarcinoma (EAC) is one of the most commonly diagnosed gynaecological malignancies among female population of the developed countries. DUSP6 is a negative regulator of ERK signaling, which is a molecular switch involved in MAPK signaling ...
Fan Ming-Jun +5 more
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Redox Report, 2022 Objective Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein in modulating versican/platelet derived growth factor (PDGF ...
Yousra M. El-Far +4 more
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Journal of Cell Biology, 2010 In this issue, a study by Groehler and Lannigan (2010. J. Cell Biol. doi:10.1083/jcb.201002124) sheds light on the regulation of proliferating cell nuclear antigen (PCNA) turnover and how it is counteracted by the small chromatin-bound kinase ERK8 (extracellular signal-regulated kinase 8). Importantly, inactivation of ERK8 results in genome instability
Nguyen, Hai Dang, Bielinsky, Anja-Katrin
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The expression of MAPK signaling pathways in conjunctivochalasis [PDF]
International Journal of Ophthalmology, 2019 This study investigated the potential role of MAPK signaling pathways in conjunctivochalasis (CCH). Twenty loose conjunctival biopsy samples from 20 CCH and 15 conjunctival biopsy samples from 15 normal controls (CON) were collected.
Yuan-Ling Jia +4 more
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S-nitrosylation of ERK inhibits ERK phosphorylation and induces apoptosis [PDF]
Scientific Reports, 2013 Extracellular signal-regulated kinase (ERK) belongs to the mitogen-activated protein kinases (MAPK) superfamily. Aberrant upregulation and activation of ERK cascades may often lead to tumor cell development. However, how ERK is involved in tumor progression is yet to be defined.
Xiujing Feng +6 more
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Molecules, 2020 Osteosarcoma, which is the most prevalent malignant bone tumor, is responsible for the great majority of bone cancer-associated deaths because of its highly metastatic potential. Although tomatidine is suggested to serve as a chemosensitizer in multidrug-
Min-Hong Hsieh +6 more
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Drug Design, Development and Therapy, 2021 Xuedong Li,1,2,* Xixi Lin,1,2,* Zuoxing Wu,3 Yuangang Su,1,2 Jiamin Liang,1,2 Runfeng Chen,1,2 Xue Yang,1,2 Lei Hou,4 Jinmin Zhao,1,5 Qian Liu,5 Feng Xu1,2,6 1Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi ...
Li X +10 more
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