Results 201 to 210 of about 204,002 (257)

Comprehensive map of the regulatory network triggered by MET exon 14 skipping reveals important involvement of the RAS-ERK signaling pathway. [PDF]

Cell Death Dis
Truong MJ, Pawlak G, Meneboo JP, Sebda S, Fernandes M, Figeac M, Elati M, Tulasne D.   +7 more
europepmc   +1 more source

Correction: VNP20009-Abvec-Igκ-MIIP suppresses ovarian cancer progression by modulating Ras/MEK/ERK signaling pathway. [PDF]

Appl Microbiol Biotechnol
Wang Q, Tang Y, Dai A, Li T, Pei Y, Zhang Z, Hu X, Chen T, Chen Q.   +8 more
europepmc   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

miR-363-5p regulates liver disease via the MAPK/ERK signaling pathway by targeting CPEB2 in chicken. [PDF]

Poult Sci
Xiang J, Jia B, Luo Z, He H, Zhang Y, Cui C, Yin H, Han S, Liu C.   +8 more
europepmc   +1 more source

Regulatory Effects of Ammonium Chloride in an In Vitro Model of Hepatic Encephalopathy: Mechanisms Involving ACTA2‐Mediated Cytoskeletal Remodeling

iLABMED, EarlyView.
Hyperammonemic stress suppresses ACTA2 expression and induces F‐actin cytoskeletal remodeling in astrocytes. The resulting inhibition of FAK/c‐Src signaling contributes to apoptosis, G2/M arrest, AQP4‐mediated swelling and junction‐associated proteins dysregulation, revealing a central role for ACTA2‐dependent cytoskeletal dysfunction in hepatic ...
Yue Tang, Jia Liu, Chengrong Bian, Wenwen Yuan, Wang Zhang, Fan Feng, Boan Li   +6 more
wiley   +1 more source

Parthenolide ameliorates glucocorticoid-induced inhibition of osteogenic differentiation and osteoporosis by activating ERK signaling pathway. [PDF]

J Orthop Surg Res
Feng Y, Li Z.
europepmc   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source

Apatinib modulates sorafenib-resistant hepatocellular carcinoma through inhibiting the EGFR/JNK/ERK signaling pathway. [PDF]

Oncol Res
Fan D, Su W, Bi Z, Wang X, Xu X, Ma M, Zhu L, Zhang Z, Gao J.   +8 more
europepmc   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Targeting <i>WTAP</i> sensitizes hepatocellular carcinoma to sorafenib by inhibiting the ERK signaling pathway. [PDF]

J Zhejiang Univ Sci B
Wu Y, Ju G, Zhou X, Wu J, Zheng S, Peng C.   +5 more
europepmc   +1 more source