Results 21 to 30 of about 9,053 (223)

Beyond the coding genome: non-coding mutations and cancer

Frontiers in Bioscience-Landmark, 2020
Latest advancements in genomics involving individuals from different races and geographical locations has led to the identification of thousands of common as well as rare genetic variants and copy number variations (CNVs). These studies have surprisingly
Kaivalya Walavalkar, Dimple Notani
doaj   +1 more source

Genetically regulated eRNA expression predicts chromatin contact frequency and reveals genetic mechanisms at GWAS loci. [PDF]

Nat Commun
Betti MJ, Lin P, Aldrich MC, Gamazon ER.
europepmc   +3 more sources

Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate

Frontiers in Cell and Developmental Biology, 2020
Enhancers are cis-regulatory elements in the genome that cooperate with promoters to control target gene transcription. Unlike promoters, enhancers are not necessarily adjacent to target genes and can exert their functions regardless of enhancer ...
Preston R. Arnold, Preston R. Arnold, Andrew D. Wells, Xian C. Li   +3 more
doaj   +1 more source

Metabarcoding monitoring analysis: the pros and cons of using co-extracted environmental DNA and RNA data to assess offshore oil production impacts on benthic communities [PDF]

PeerJ, 2017
Sequencing environmental DNA (eDNA) is increasingly being used as an alternative to traditional morphological-based identification to characterize biological assemblages and monitor anthropogenic impacts in marine environments.
Olivier Laroche, Susanna A. Wood, Louis A. Tremblay, Gavin Lear, Joanne I. Ellis, Xavier Pochon   +5 more
doaj   +2 more sources

Metabarcoding by Combining Environmental DNA with Environmental RNA to Monitor Fish Species in the Han River, Korea

Fishes, 2023
Fishes are ecologically important organisms that have long lifespans, high mobilities, and diverse trophic levels. Due to their importance, fishes are used as bioindicators for monitoring aquatic environments. One method for monitoring fishes is based on
Hyung-Eun An, Min-Ho Mun, Chang-Bae Kim
doaj   +1 more source

Environmental RNA as a Tool for Marine Community Biodiversity Assessments

Scientific Reports, 2022
Microscopic organisms are often overlooked in traditional diversity assessments due to the difficulty of identifying them based on morphology. Metabarcoding is a method for rapidly identifying organisms where Environmental DNA (eDNA) is used as a ...
Marissa S. Giroux, Jay R. Reichman, Troy Langknecht, Robert M. Burgess, Kay T. Ho   +4 more
doaj   +1 more source

Tunable degree of polarization in a figure-8 fiber laser

AIP Advances, 2022
We experimentally study a fiber loop laser in a figure-8 configuration and explore the dependency of the degree of polarization on controlled parameters. To account for the experimental observations, a mapping is derived to evaluate the polarization time
Banoj Kumar Nayak, Cijy Mathai, Dmitry Panna, Eyal Buks   +3 more
doaj   +1 more source

Wanted dead or alive? Using metabarcoding of environmental DNA and RNA to distinguish living assemblages for biosecurity applications. [PDF]

PLoS ONE, 2017
High-throughput sequencing metabarcoding studies in marine biosecurity have largely focused on targeting environmental DNA (eDNA). DNA can persist extracellularly in the environment, making discrimination of living organisms difficult.
Xavier Pochon, Anastasija Zaiko, Lauren M Fletcher, Olivier Laroche, Susanna A Wood   +4 more
doaj   +1 more source

Self-extracellular RNA promotes pro-inflammatory response of astrocytes to exogenous and endogenous danger signals

Journal of Neuroinflammation, 2021
Objective Astrocytes participate in the local innate immune response of the central nervous system. In response to stress such as ischemia, activated cells release endogenous factors known as damage-associated molecular patterns (DAMPs).
Silvia Fischer, Emil Nasyrov, Monika Brosien, Klaus T. Preissner, Hugo H. Marti, Reiner Kunze   +5 more
doaj   +1 more source

Molecular Mechanism of Mulberrin Regulating Lipid Metabolism Homeostasis Based on the Gut–Liver Axis Fiaf/AMPK Signaling Pathway

Food Frontiers, EarlyView.
The molecular mechanism for mulberrin regulating lipid metabolism homeostasis. ABSTRACT Lipid metabolism disorders and the induced metabolic diseases have risen to become one of the primary public health issues. Our preliminary experimental results confirmed that mulberry leaf flavonoid extract exhibited efficacy in lipid metabolism regulation; the ...
Qian Li, Daorui Pang, Erna Li, Dongxu Xing, Fan Liu, Li Wang, Yuxiao Zou   +6 more
wiley   +1 more source