Results 51 to 60 of about 1,193,962 (294)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Technical note: Isotopic fractionation of evaporating waters: effect of sub-daily atmospheric variations and eventual depletion of heavy isotopes [PDF]

Hydrology and Earth System Sciences
Isotopic fractionation of evaporating waters has been studied constantly in recent decades, particularly because it enables calculation of both the volume of water evaporated from a water body and the isotopic composition of its source water.
F. Gallart, S. González-Fuentes, P. Llorens   +2 more
doaj   +1 more source

Exogenous melatonin alleviates PEG-induced short-term water deficiency in maize by increasing hydraulic conductance

BMC Plant Biology, 2020
Background Water deficiency is likely to become more frequent and intense as a result of global climate change, which may severely impact agricultural production in the world.
Yujie Qiao, Jianhong Ren, Lina Yin, Yijian Liu, Xiping Deng, Peng Liu, Shiwen Wang   +6 more
doaj   +1 more source

Regional Farmers’ Perception and Societal Issues in Vineyards Affected by High Erosion Rates

Land, 2021
We explore the current situation in a viticultural region in Eastern Spain from a holistic and multifaceted research approach, which allowed us to understand the biophysical conditions, economic cost, social impact, and perception of the farmers ...
Artemi Cerdà, Jesús Rodrigo-Comino
doaj   +1 more source

Erosion-corrosion maps for carbon steel in crude oil/water slurries : impact angle and applied potential effects [PDF]

, 2010
In studies of erosion-corrosion, there have been few investigations into the effect of tribological issues, such as particle impact and impact angle, on erosion-corrosion of materials in oil field production.
Abdulrahman, G.H., Stack, M.M.
core  

A scenario of planet erosion by coronal radiation [PDF]

, 2009
Context: According to theory, high-energy emission from the coronae of cool stars can severely erode the atmospheres of orbiting planets. No observational tests of the long term effects of erosion have yet been made.
A. M. T. Pollock, C. Eiroa, Cecchi-Pestellini, Cnossen, D. García-Álvarez, Davis, E. Solano, Els, Erkaev, Favata, G. Micela, García Muñoz, Grießmeier, Hubbard, I. Ribas, J. Sanz-Forcada, Kashyap, Lagrange, Lammer, Lecavelier Des Etangs, Mugrauer, Orlando, Penz, Penz, Pizzolato, Ribas, Sanz-Forcada, Sanz-Forcada, Tian, Watson, Yelle   +30 more
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Effect of microstructure and temperature on the erosion rates and mechanisms of modified EB PVD TBCs [PDF]

, 2009
Thermal barrier coatings (TBCs) have now been used in gas turbine engines for a number of decades and are now considered to be an accepted technology. As there is a constant drive to increase the turbine entry temperature, in order to increase engine ...
Murphy, K. S., Nicholls, J. R., Wellman, R. G.   +2 more
core   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source