Results 121 to 130 of about 2,468,151 (278)

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

Advanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton, Carrillo Paola Gonzalez, Luay Almassalha, Wing Shun Li, Ruyi Gong, Nicolas Acosta, I Chae Ye, Jane Frederick, Christopher Hogg, Saira John, J. A. Gareth Williams, Rikkert J. Nap, Igal Szleifer, Vadim Backman   +13 more
wiley   +1 more source

Long‐Chain Molecule Reconstruction of Novel Solvation Structure to Stabilize Zinc Metal Anode

Advanced Science, EarlyView.
Triethylene glycol diacetate (TGD), with unique long‐chain characteristics and rich oxygen‐containing functional groups, was used as an electrolyte additive to reconstruct the solvation structure. TGD can reduce the erosion of H2O molecules on the Zn anode, effectively homogenize the electric field distribution. Therefore, the Zn//Zn symmetric cell can
Changdong Chen, Lingwei Xue, Gaojie Li, Xueli Chen, Yongjun Han, Liwei Mi, Yuqing Chen   +6 more
wiley   +1 more source

Beyond Traditional Phenolics: Disulfide Bonds for Performance Enhancement of Aerospace Ablation‐Resistant Materials from Processing to Recycling

Advanced Science, EarlyView.
The dynamic disulfide bonds facilitated the development of high‐performance aerospace ablation‐resistant materials. At moderate temperature, the dissociation and recombination of disulfide bonds ensured excellent processability, mechanical properties, and recycling ability of phenolic resin; at high temperature, cleavage of disulfide bonds produced ...
Yu Li, Boyuan Hu, Xiaolong Xing, Huan Yang, Ziqi Zhang, Cheng Bian, Ruixue Bai, Ling Yue, Chengshuang Zhang, Xinli Jing   +9 more
wiley   +1 more source

Toward High‐Resolution Polymeric Neural Interfaces: A Practical Guide for Electron Beam Lithography

Advanced Science, EarlyView.
Electron beam lithography (EBL) enables sub‐micron patterning of polymer‐based neural implants, overcoming the resolution limits of optical lithography. By addressing challenges such as charging, non‐planarity, and substrate heating, it supports higher channel density, improved miniaturization, and better long‐term tissue integration.
Hanna Karlsson‐Fernberg, Maria Asplund
wiley   +1 more source

Groundwater Rise Sustains the World's Largest Alpine Water System Under Global Warming

Advanced Science, EarlyView.
Shallow groundwater depth (SGWD) across the non‐permafrost plains of the Qinghai–Xizang Plateau decreased at averagely 0.02 m year−1, adding 31.44 Gt of freshwater storage from 2000 to 2020 and sustaining ∼53 500 km2 of alpine ecosystems. A vadose‐zone capacity of 426.6 Gt reveals these aquifers as promising reservoirs, highlighting groundwater's ...
Jianqing Du, Zhixiang Niu, Yanfen Wang, Shirui Zhou, Youqing Yang, Xiang Wei, Haishan Niu, Yitao Zhang, Anquan Xia, Yali Liu, Yanbin Hao, Kai Xue, Bingfang Wu, Xinquan Zhao, Tandong Yao, Yiyu Chen   +15 more
wiley   +1 more source

Bio‐Inspired Gradient Coatings Enhance the Leading Edge Erosion Resistance of Wind Blades

Advanced Science, EarlyView.
Rain‐induced erosion of the wind turbine blade leading edge poses a critical challenge to maintenance and operation. Here, we propose a bio‐inspired approach for erosion protection utilising a platelet‐reinforced polyurethane coating with a graded through‐thickness architecture.
Natalia Sofia Guevara‐Sotelo, Julie Teuwen, Kunal Masania   +2 more
wiley   +1 more source

NiH‐Catalyzed Enantio‐ and Regioselective Hydroselenylation of Unactivated Alkenes

Advanced Science, EarlyView.
Nickel‐hydride‐catalyzed enantio‐ and regioselective hydroselenylation of unactivated alkenes provides access to chiral organoselenium compounds. Enantiodetermining Ni–H insertion followed by single‐electron diselenide activation generates selenyl radical.
Hyung‐Joon Kang, Jaehun Kim, Sungwoo Hong   +2 more
wiley   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source