Results 131 to 140 of about 82,940 (314)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Component-by-component construction of good intermediate-rank lattice rules

, 2003
It is known that the generating vector of a rank-1 lattice rule can be constructed component-by-component to achieve strong tractability error bounds in both weighted Korobov spaces and weighted Sobolev spaces.
Joe, Stephen, Kuo, Frances Y.
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Some New and Sharp Inequalities of Composite Simpson’s Formula for Differentiable Functions with Applications

Mathematics
Composite integral formulas offer greater accuracy by dividing the interval into smaller subintervals, which better capture the local behavior of function. In the finite volume method for solving differential equations, composite formulas are mostly used
Wei Liu, Yu Wang, Ifra Bashir Sial, Loredana Ciurdariu   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Error Estimation of Weddle’s Rule for Generalized Convex Functions with Applications to Numerical Integration and Computational Analysis

Mathematics
This paper presents new integral inequalities for differentiable generalized convex functions in the second sense, with a focus on improving the accuracy of Weddle’s formula for numerical integration.
Abdul Mateen, Bandar Bin-Mohsin, Ghulam Hussain Tipu, Asia Shehzadi   +3 more
doaj   +1 more source

An Inequality of Ostrowski-Grüss Type for Twice Differentiable Mappings and Applications in Numerical Integration

, 1998
In this paper we derive a new integral inequality of Ostrowski-Grüss type and apply it to estimate the error bounds for some numerical quadrature ...
Roumeliotis, John, Cerone, Pietro, Dragomir, Sever S   +2 more
core  

Nonlinear error bounds for quasiconvex inequality systems

, 2017
The error bound is an inequality that restricts the distance from a vector to a given set by a residual function. The error bound has so many useful applications, for example in variational analysis, in convergence analysis of algorithms, in sensitivity ...
Kuroiwa, Daishi, Suzuki, Satoshi
core   +1 more source