Results 111 to 120 of about 1,846,959 (284)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Further Fractional Hadamard Integral Inequalities Utilizing Extended Convex Functions

Fractal and Fractional
This work investigates novel fractional Hadamard integral inequalities by utilizing extended convex functions and generalized Riemann-Liouville operators.
Areej A. Almoneef, Mohamed A. Barakat, Abd-Allah Hyder   +2 more
doaj   +1 more source

Error Bounds for Lagrange Interpolation

Journal of Approximation Theory, 1995
Consider an interpolation of functions \(f\in W_ \infty^ m [a,b]\) by Lagrange polynomials \(\ell_{m-1}\), \(\Delta(f)\) of degree \(m-1\) at the mesh \(\Delta\) of the interpolating nodes \(\{t_ j\}^ m_ 1\). Error bounds due to this approximation is evaluated as \[ L_{m,k} (\Delta)= \sup_{x\in [a,b]} L_{m,k} (\Delta,x)= {\textstyle {1\over m ...
openaire   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Asymptotic Behavior of the Modulus of the Kernel and Error Bounds of Anti-Gaussian Quadrature Formulas with Jacobi Weights

Mathematics
In this paper, the remainder term of anti-Gaussian quadrature rules for analytic integrands with respect to Jacobi weight functions ωa,b(x)=(1−x)a(1+x)b, where a,b>−1, is analyzed, and sharp estimates of the error are provided.
Ramon Orive, Ljubica Mihić, Aleksandar Pejčev, Miroslav Pranić, Stefan Spalević   +4 more
doaj   +1 more source

Error bounds for eigenvectors of self-adjoint operators

, 1962
Error estimates are given for ||ui-phi||, where ui is a normalized eigenvector of a selfadjoint operator A and phi is a normalized approximating vector.
Bazley, Norman W.; Fox, David W.
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source