Results 121 to 130 of about 5,389,818 (356)

Error filtering, pair assembly and error correction for next-generation sequencing reads

Bioinform., 2015
MOTIVATION Next-generation sequencing produces vast amounts of data with errors that are difficult to distinguish from true biological variation when coverage is low.
Robert C. Edgar, H. Flyvbjerg
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Criticality Aware Soft Error Mitigation in the Configuration Memory of SRAM based FPGA

, 2018
Efficient low complexity error correcting code(ECC) is considered as an effective technique for mitigation of multi-bit upset (MBU) in the configuration memory(CM)of static random access memory (SRAM) based Field Programmable Gate Array (FPGA) devices ...
Chakrabarti, Amlan, Chattopadhyay, Anupam, Mandal, Swagata, Ming, Wong Ming, Sarkar, Sreetama   +4 more
core   +1 more source

Neural Grammatical Error Correction Systems with Unsupervised Pre-training on Synthetic Data

BEA@ACL, 2019
Considerable effort has been made to address the data sparsity problem in neural grammatical error correction. In this work, we propose a simple and surprisingly effective unsupervised synthetic error generation method based on confusion sets extracted ...
Roman Grundkiewicz, Marcin Junczys-Dowmunt, Kenneth Heafield   +2 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Quantum Error Correction in Scrambling Dynamics and Measurement-Induced Phase Transition.

Physical Review Letters, 2019
We analyze the dynamics of entanglement entropy in a generic quantum many-body open system from the perspective of quantum information and error corrections.
Soonwon Choi, Yimu Bao, X. Qi, E. Altman
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

PREMIER - PRobabilistic Error-correction using Markov Inference in Errored Reads [PDF]

, 2013
In this work we present a flexible, probabilistic and reference-free method of error correction for high throughput DNA sequencing data. The key is to exploit the high coverage of sequencing data and model short sequence outputs as independent ...
Dorman, Karin, Ramamoorthy, Aditya, Ramamoorthy, Aditya, Song, Zhao, Yin, Xin   +4 more
core   +3 more sources

Continuous quantum error correction for non-Markovian decoherence

, 2007
We study the effect of continuous quantum error correction in the case where each qubit in a codeword is subject to a general Hamiltonian interaction with an independent bath. We first consider the scheme in the case of a trivial single-qubit code, which
A. Barenco, D. Aharonov, H.-P. Breuer, J. P. Paz, M. Sarovar, Ognyan Oreshkov, P. Aliferis, P. Shor, Todd A. Brun   +8 more
core   +1 more source