Results 101 to 110 of about 1,041,335 (309)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
A Swiss cheese error detection method for real-time EPID-based quality assurance and error prevention. [PDF]
, 2017 PURPOSE To develop a robust and efficient process that detects relevant dose errors (dose errors of ≥5%) in external beam radiation therapy and directly indicates the origin of the error.
Passarge, Michelle +4 more
core +1 more source
Informatics, 2019 Translation revision is a relevant topic for translator training and research. Recent technological developments justify increased focus on embedding speech technologies—speech synthesis (text-to-speech) and speech recognition (speech-to-text ...
Dragoş Ciobanu +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
A Redundant Residue Number System Coded Burst-by-Burst Adaptive Joint-Detection Based CDMA Speech Transceiver [PDF]
, 2006 A burst-by-burst (BbB) adaptive speech transceiver is proposed, which can drop its source coding rate and speech quality under transceiver control in order to invoke a more error resilient modem mode among less favorable channel conditions.
H.T. How +9 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Error Detection and Recovery Techniques for Variation-Aware CMOS Computing: A Comprehensive Review
Journal of Low Power Electronics and Applications, 2011 While Moore’s law scaling continues to double transistor density every technology generation, new design challenges are introduced. One of these challenges is variation, resulting in deviations in the behavior of transistors, most importantly in ...
Joseph Crop +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Performance Monitoring Applied to System Supervision
Frontiers in Human Neuroscience, 2017 Nowadays, automation is present in every aspect of our daily life and has some benefits. Nonetheless, empirical data suggest that traditional automation has many negative performance and safety consequences as it changed task performers into task ...
Bertille Somon +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source