Results 131 to 140 of about 1,205,694 (316)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Efficient automated error detection in medical data using deep-learning and label-clustering. [PDF]

open access: yesSci Rep, 2023
Nguyen TV   +6 more
europepmc   +1 more source

Robot Error Awareness Through Human Reactions: Implementation, Evaluation, and Recommendations [PDF]

open access: yesarXiv
Effective error detection is crucial to prevent task disruption and maintain user trust. Traditional methods often rely on task-specific models or user reporting, which can be inflexible or slow. Recent research suggests social signals, naturally exhibited by users in response to robot errors, can enable more flexible, timely error detection.
arxiv  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Too Consistent to Detect: A Study of Self-Consistent Errors in LLMs [PDF]

open access: yesarXiv
As large language models (LLMs) often generate plausible but incorrect content, error detection has become increasingly critical to ensure truthfulness. However, existing detection methods often overlook a critical problem we term as self-consistent error, where LLMs repeatly generate the same incorrect response across multiple stochastic samples. This
arxiv  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Deep Learning-Based Boolean, Time Series, Error Detection, and Predictive Analysis in Container Crane Operations

open access: yesAlgorithms
Deep learning is crucial in marine logistics and container crane error detection, diagnosis, and prediction. A novel deep learning technique using Long Short-Term Memory (LSTM) detected and anticipated errors in a system with imbalanced data.
Amruta Awasthi   +2 more
doaj   +1 more source

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