Results 151 to 160 of about 2,569,797 (292)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A Deep-Learning Error Detection System in Radiation Therapy. [PDF]

Ann Biomed Res, 2023
Kump PM, Xia J, Yaddanapudi S, Bai E.
europepmc   +1 more source

Lex-Pos Feature-Based Grammar Error Detection System for the English Language [PDF]

, 2020
Nancy Agarwal, Mudasir Ahmad Wani, Patrick Bours   +2 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The DetectDeviatingCells algorithm was a useful addition to the toolkit for cellwise error detection in observational data. [PDF]

J Clin Epidemiol, 2023
Viviani L, White IR, Williamson EJ, Carpenter J, van der Meulen J, Cromwell DA.   +5 more
europepmc   +1 more source

Combining GCN and Transformer for Chinese Grammatical Error Detection

, 2022
Jinhong Zhang Jinhong Zhang
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

[ITAL]ROSAT[/ITAL] Detection and High-Precision Localization of X-Ray Sources in the 1978 November 19 Gamma-Ray Burst Error Box [PDF]

, 1997
M. Boër, C. Motch, J. Greiner, W. Voges, P. Kahabka, H. Pedersen   +5 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Radiotherapy delivery error detection with electronic portal imaging device (EPID)-based in vivo dosimetry. [PDF]

Chin Med J (Engl), 2023
Yang X, Geng L, Huang D, Li K, Zhuang H, Cai J, Yang R.   +6 more
europepmc   +1 more source