Results 51 to 60 of about 1,666,189 (240)
Nonparametric Functional Least Absolute Relative Error Regression: Application to Econophysics
MathematicsIn this paper, we propose an alternative kernel estimator for the regression operator of scalar response variable S given a functional random variable T that takes values in a semi-metric space.
Ali Laksaci +2 more
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Understanding and reducing errors in density functional calculations
, 2013 We decompose the energy error of any variational DFT calculation into a contribution due to the approximate functional and that due to the approximate density.
Burke, Kieron +2 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
New Error Coefficients for Estimating Quadrature Errors for Analytic Functions [PDF]
Mathematics of Computation, 1970 Since properly normalized Chebyshev polynomials of the first kind T ~ n ( Z ) {\tilde T_n}(Z) satisfy \[ ( T ~
Rabinowitz, P., Richter, N.
openaire +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Functional a posteriori error estimates for parabolic time-periodic boundary value problems [PDF]
, 2014 The paper is concerned with parabolic time-periodic boundary value problems which are of theoretical interest and arise in different practical applications. The multiharmonic finite element method is well adapted to this class of parabolic problems.
Langer, Ulrich +2 more
core
Learning from your mistakes: The functional value of spontaneous error monitoring in aphasia
Frontiers in Psychology, 2014 Self-monitoring of errors in picture naming has been shown to correlate positively with aphasia treatment outcomes (Marshall et al., 1994). To explore potential explanations, we took advantage of aphasics’ item-level inconsistency in naming accuracy, e ...
Erica L. Middleton +3 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source