Results 131 to 140 of about 1,871,213 (304)

Taybi and Lachman's radiology of syndromes, metabolic disorders, and skeletal dysplasias /

open access: yes, 2007
Revised edition of: Radiology of syndromes, metabolic disorders, and skeletal dysplasias / Hooshang Taybi, Ralph S. Lachman. 4th ed. St.
Taybi, HooshangRadiology of syndromes, metabolic disorders, and skeletal dysplasias.   +1 more
core  

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

open access: yesAdvanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu   +13 more
wiley   +1 more source

Case report: A germline CHEK1 c.613 + 2T>C leads to a splicing error in a family with multiple cancer patients

open access: yesFrontiers in Oncology
BackgroundGenome instability plays a crucial role in promoting tumor development. Germline mutations in genes responsible for DNA repair are often associated with familial cancer syndromes. A noticeable exception is the CHEK1 gene.
Jun Qian   +8 more
doaj   +1 more source

Efficient Board-Level Functional-Fault Diagnosis with Missing Syndromes

open access: yes, 2015
Functional fault diagnosis is widely used in board manufacturing to ensure product quality and improve product yield. Advanced machine-learning techniques have recently been advocated for reasoning-based diagnosis; these techniques are based on the ...
Jin, S   +4 more
core  

A longitudinal study of abnormalities on MRI and disability from multiple sclerosis [PDF]

open access: yes, 2002
Background: In patients with isolated syndromes that are clinically suggestive of multiple sclerosis, such as optic neuritis or brain-stem or spinal cord syndromes, the presence of lesions as determined by T2-weighted magnetic resonance imaging (MRI) of ...
Ciccarelli, O.   +5 more
core  

Cranial Neuropathies & Brainstem Syndromes

open access: yes, 2017
This chapter addresses the various cranial neuropathies and brainstem syndromes and their respective anatomical components. Included among these disorders are pupillary reflex pathologies, oral-palatal deviations, gag reflex, facial palsy, Bell’s palsy ...
Adam J Fisch
core   +1 more source

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

open access: yesAdvanced Science, EarlyView.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han   +10 more
wiley   +1 more source

Closed-form approximations to the Error and Complementary Error Functions and their applications in atmospheric science. [PDF]

open access: yes, 2007
The Error function, and related functions, occurs in theoretical aspects of many parts of atmospheric science. This note presents a closed-form approximation for the error, complementary error, and scaled complementary error functions, with maximum ...
MacKenzie, Rob, Ren, Chuansen
core   +1 more source

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye   +6 more
wiley   +1 more source

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

open access: yesAdvanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu   +8 more
wiley   +1 more source

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