Results 81 to 90 of about 208,269 (282)

Hybrid Cat-Transmon Architecture for Scalable, Hardware-Efficient Quantum Error Correction

PRX Quantum
Dissipative cat qubits are a promising physical platform for quantum computing, since their large noise bias can enable more hardware-efficient quantum error correction. In this work we theoretically study the long-term prospects of a hybrid cat-transmon
Connor T. Hann, Kyungjoo Noh, Harald Putterman, Matthew H. Matheny, Joseph K. Iverson, Michael T. Fang, Christopher Chamberland, Oskar Painter, Fernando G.S.L. Brandão   +8 more
doaj   +1 more source

Hardness results for decoding the surface code with Pauli noise [PDF]

Quantum
Real quantum computers will be subject to complicated, qubit-dependent noise, instead of simple noise such as depolarizing noise with the same strength for all qubits.
Alex Fischer, Akimasa Miyake
doaj   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Quantum computer error structure probed by quantum error correction syndrome measurements

Physical Review Research
With quantum devices rapidly approaching qualities and scales needed for fault tolerance, the validity of simplified error models underpinning the study of quantum error correction needs to be experimentally evaluated. In this work, we have assessed the performance of IBM superconducting quantum computer devices implementing heavy-hexagon code syndrome
Spiro Gicev, Lloyd C. L. Hollenberg, Muhammad Usman   +2 more
openaire   +3 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Neonatal Seizures: When to Consider and How to Investigate for an Inborn Error of Metabolism

Proceedings of Singapore Healthcare, 2010
Seizures occur more frequently in the neonatal period than in the remainder of childhood. Neonatal seizures can have different aetiologies. Inborn errors of metabolism are rare causes of seizures in the newborn.
Derrick Wei Shih Chan B Med Sci, MRCPCH (UK), Ee Shien Tan MBBS, MRCPCH (UK), Maureen Anne Cleary MD, MRCP (UK)   +2 more
doaj   +1 more source

Quantum Computer Fingerprinting using Error Syndromes

As quantum computing matures and moves toward broader accessibility through cloud-based platforms, ensuring the authenticity and integrity of quantum computations becomes an urgent concern. In this work, we propose a strategy to leverage the byproducts of quantum error correction (QEC) to verify hardware identity and authenticate quantum computations ...
Mutolo, Vincent, Campbell, Devon, Manning, Quinn, Dubourg, Henri Witold, Lyu, Ruibin, Sethumadhavan, Simha, Rubenstein, Daniel, Stolfo, Salvatore   +7 more
openaire   +2 more sources

Malformation syndromes due to inborn errors of cholesterol synthesis [PDF]

Journal of Clinical Investigation, 2002
Cholesterol has long been known to function as both a structural lipid and a precursor molecule for bile acid and steroid hormone synthesis. In addition, this ubiquitous lipid is now known to contribute fundamentally to the development and function of the CNS and the bones, and, as detailed in other articles in this Perspective series, it plays major ...
openaire   +2 more sources