Results 81 to 90 of about 2,032,232 (300)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Effects of errors-in-variables on the internal and external reliability measures

open access: yesGeodesy and Geodynamics
The reliability theory has been an important element of the classical geodetic adjustment theory and methods in the linear Gauss-Markov model. Although errors-in-variables (EIV) models have been intensively investigated, little has been done about ...
Yanxiong Liu   +4 more
doaj   +1 more source

Total least-squares EIO model, algorithms and applications

open access: yesGeodesy and Geodynamics, 2019
A functional model named EIO (Errors-In-Observations) is proposed for general TLS (total least-squares) adjustment. The EIO model only considers the correction of the observation vector, but doesn't consider to correct all elements in the design matrix ...
Xingsheng Deng   +3 more
doaj   +1 more source

Fast and robust estimation of the multivariate errors in variables model. [PDF]

open access: yes
In the multivariate errors in variable models one wishes to retrieve a linear relationship of the form y = ß x + a, where both x and y can be multivariate. The variables y and x are not directly measurable, but observed with measurement error.
Croux, Christophe   +2 more
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Evaluation of the Weak Constraint Data Assimilation Approach for Estimating Turbulent Heat Fluxes at Six Sites

open access: yesRemote Sensing, 2018
A number of studies have estimated turbulent heat fluxes by assimilating sequences of land surface temperature (LST) observations into the strong constraint-variational data assimilation (SC-VDA) approaches.
Xinlei He   +8 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Confidence Region for Calibration Function Coefficients

open access: yesMeasurement Science Review, 2018
The paper deals with the comparative calibration model, i.e. with a situation when both variables are subject to errors. The calibration function is supposed to be a polynomial.
Ráboňová Petra, Wimmer Gejza
doaj   +1 more source

Life-Cycle Variation in the Association between Current and Lifetime Earnings [PDF]

open access: yes
Researchers in a variety of important economic literatures have assumed that current income variables as proxies for lifetime income variables follow the textbook errors-in-variables model.
Gary Solon, Steven Haider
core  

Statistical Models with Uncertain Error Parameters

open access: yes, 2019
In a statistical analysis in Particle Physics, nuisance parameters can be introduced to take into account various types of systematic uncertainties. The best estimate of such a parameter is often modeled as a Gaussian distributed variable with a given ...
Cowan, Glen
core   +1 more source

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