Results 81 to 90 of about 8,978,880 (312)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Accruals, Investment and Errors-in-Variables [PDF]

We formulate well-known discretionary accruals models in an investment setting. Given that accruals basically consist of short-term investment, we introduce, (i) cash-flows, as a proxy for financial constraints and other financial markets imperfections ...
Francois Racicot, Christian Calmès, Denis Cormier, Raymond Théoret   +3 more
core  

Effects of errors-in-variables on the internal and external reliability measures

Geodesy and Geodynamics
The reliability theory has been an important element of the classical geodetic adjustment theory and methods in the linear Gauss-Markov model. Although errors-in-variables (EIV) models have been intensively investigated, little has been done about ...
Yanxiong Liu, Yun Shi, Peiliang Xu, Wenxian Zeng, Jingnan Liu   +4 more
doaj   +1 more source

Evaluation of the Weak Constraint Data Assimilation Approach for Estimating Turbulent Heat Fluxes at Six Sites

Remote Sensing, 2018
A number of studies have estimated turbulent heat fluxes by assimilating sequences of land surface temperature (LST) observations into the strong constraint-variational data assimilation (SC-VDA) approaches.
Xinlei He, Tongren Xu, Sayed M. Bateni, Christopher M. U. Neale, Thomas Auligne, Shaomin Liu, Kaicun Wang, Kebiao Mao, Yunjun Yao   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

3D reconstruction based on pseudo-linearization and errors-in-variables model

, 2006
This paper proposes a general approach of 3D reconstruction, a major problem arising in computer vision and virtual reality, based on a combination of Pseudo-Linearization and Errors-in-Variables model. The proposed approach concerns a bunch of corrupted
Shi ZL(史泽林), Hou TB(侯庭波), Wang JW(汪俊文), Zhu F(朱枫)   +3 more
core  

Confidence Region for Calibration Function Coefficients

Measurement Science Review, 2018
The paper deals with the comparative calibration model, i.e. with a situation when both variables are subject to errors. The calibration function is supposed to be a polynomial.
Ráboňová Petra, Wimmer Gejza
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Errors in variables and lending discrimination [PDF]

Consumer credit ; Discrimination in consumer ...
Jed L. DeVaro, Jeffrey M. Lacker
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source