Results 111 to 120 of about 13,873 (221)

Prenatal diagnosis of β-thalassaemia using fetal erythroblasts enriched from maternal blood by a novel gradient [PDF]

, 2000
We have assessed a new technique for the isolation of fetal erythroblasts from maternal blood for the non-invasive prenatal diagnosis of pregnancies at risk of β-thalassaemia.
TANNOIA, Nunzia, D'ADDARIO, Vincenzo, Campanale, Daniela, Holzgreve, Wolfgang, Hahn, Sinuhe, Vitucci, Angelantonio, DI NARO, Edoardo, Ghezzi, Fabio   +7 more
core  

ACTH enhances enucleation of erythroblasts derived from human HPCs.

, 2015
(A) The neutralization of melanocortins by addition of the neutralising antibodies (nAbs) for ACTH and α-MSH into culture media on the M0 day and the M3 day. The enucleation rate on the M5 day was measured. *, P < 0.01. n = 3; error bars, s.e.m. (B) Cell
Hiroko Masuta (720233), Eriko Simamura (720229), Hiroki Otani (720235), Tomohiro Arikawa (121124), Hiroki Shoji (720232), Takayuki Ikeda (720230), Toshihisa Hatta (720237), Yuriko Nakajima (720234), Hiroki Shimada (720231), Hideto Yonekura (720236)   +9 more
core   +1 more source

MCRs differentially regulate EPO-induced phosphorylation of ERK, STAT5 and AKT in erythroblasts during differentiation.

, 2015
(A) Phosphorylation of ERK, STAT and AKT in erythroblasts. Erythroblasts at M0, M3 and M6 were starved for 3 h in HPGM without cofactors and subsequently incubated for 15 min with or without EPO.
Hiroko Masuta (720233), Eriko Simamura (720229), Hiroki Otani (720235), Tomohiro Arikawa (121124), Hiroki Shoji (720232), Takayuki Ikeda (720230), Toshihisa Hatta (720237), Yuriko Nakajima (720234), Hiroki Shimada (720231), Hideto Yonekura (720236)   +9 more
core   +1 more source

Metabolic reprogramming during ineffective erythropoiesis in β-thalassemia/HbE disease

Experimental and Molecular Pathology
Ineffective erythropoiesis, the main cause of anemia in β-thalassemia disease, is characterized by dramatic expansion of erythroblasts and increased erythroblast cell death.
Chanyanat Sukhuma, Donny Nauphar, Khanita Nuamsee, Wasinee Kheansaard, Kittiphong Paiboonsukwong, Alisa Wilantho, Chumpol Ngamphiw, Pornthip Chaichompoo, Sissades Tongsima, Saovaros Svasti, Phatchariya Phannasil   +10 more
doaj   +1 more source

Garland of Erythroblasts Around Macrophage: The Erythroblastic Island

Turkish Journal of Hematology, 2019
Chandan Kumar, Garima Jain, Anita Chopra
openaire   +3 more sources

HMGA2 Moderately Increases Fetal Hemoglobin Expression in Human Adult Erythroblasts.

, 2016
Induction of fetal hemoglobin (HbF) has therapeutic importance for patients with beta-hemoglobin disorders. Previous studies showed that let-7 microRNAs (miRNAs) are highly regulated in erythroid cells during the fetal-to-adult developmental transition ...
Antoinette Rabel, Jaira F. de Vasconcellos (431552), Antoinette Rabel (431554), Y. Terry Lee (431549), Colleen Byrnes, Laxminath Tumburu (838025), Colleen Byrnes (431551), Laxminath Tumburu, Jaira F de Vasconcellos, Jeffery L. Miller (431556), Jeffery L Miller, Y Terry Lee   +11 more
core   +1 more source

Investigation of Mitochondrial Transfer between Human Erythroblasts

, 2019
The increasingly studied phenomenon of mitochondria transferring between cells contrasts the popular belief that mitochondria reside permanently within their cells of origin.
Lewer, Brittany (11806112), Lewer, Brittany   +1 more
core   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts

The molecular mechanisms involved in the terminal differentiation of erythroblasts have been elucidated by comparing enucleation and cell division. Although various similarities and differences between erythroblast enucleation and cytokinesis have been ...
Kobayashi, Isuzu, Goto, Tatsufumi, Asanuma, Ken, Takahashi, Naoto, Sawada, Kenichi, Wakui, Hideki, Guo, Yong-Mei, Sasaki, Yumi, Ubukawa, Kumi   +8 more
core   +2 more sources

Single-cell transcriptome sequencing reveals the mechanism of Realgar improvement on erythropoiesis in mice with myelodysplastic syndrome

Cancer Cell International
Myelodysplastic syndrome (MDS) is a malignant hematologic disorder with limited curative options, primarily reliant on hematopoietic stem cell transplantation. Anemia, a prevalent symptom of MDS, has few effective treatment strategies.
Hao Xu, Kexin Hu, Yanlu Wang, Shuyang Cai, Fan Wu, Jizhang Bao, Qi Hu, Yu Guan, Yuchen Tao, Jiahui Lu   +9 more
doaj   +1 more source