Results 171 to 180 of about 220,414 (244)
Cold Agglutinin-Mediated Hemolysis as an Extrapulmonary Manifestation of Mycoplasma pneumoniae Infection: A Case Report. [PDF]
CureusVasconcelos SI +4 more
europepmc +1 more source
Advanced Science, EarlyView.This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong +13 more
wiley +1 more source
Advanced Science, EarlyView.Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen +12 more
wiley +1 more source
Erythrocyte membrane nervonic acid in drug-naive first-episode psychosis and chronic medicated schizophrenia: Implication for impaired myelination and prognosis. [PDF]
World J PsychiatryKhan MM.
europepmc +1 more source
Advanced Science, EarlyView.This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang +12 more
wiley +1 more source
Acute effect of tetracycline on systemic stress markers and organ histopathology in juvenile Nile tilapia, <i>Oreochromis niloticus</i>. [PDF]
Toxicol RepAl-Emran M +9 more
europepmc +1 more source
cDC1 Subtype‐Specific In Vivo Targeting of Liposomes
Advanced Science, EarlyView.Dendritic cells, particularly the cDC1 subtype, offer a promising target for drug delivery via liposomes due to their pivotal role in immune regulation, allowing for amplified therapeutic responses. Herein, we show an integration of physicochemical characterization and cell experiments to achieve effective in vivo cDC1 targeting through anti‐CLEC9A ...
Maximilian Schaaf +11 more
wiley +1 more source
The Effect of Bevacizumab Therapy on Reducing Erythrocyte Transfusion Requirements and Preventing Iron Deficiency in Patients With Hereditary Hemorrhagic Telangiectasia. [PDF]
CureusAydın Ö +10 more
europepmc +1 more source