Results 251 to 260 of about 272,635 (316)

Loss of erythrocyte arginase-1 impairs vasorelaxation due to endothelial GSNOR overexpression and denitrosylation of G protein subunits. [PDF]

Redox Biol
Gogiraju R, Sun B, Bochenek ML, Wittig I, Rezende F, Lopez M, Wirth A, Zhao W, Böhm EW, Guliani P, Moiko K, Molitor M, Wenzel P, Freichel M, Lurz P, Brandes RP, Schäfer K.   +16 more
europepmc   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Animals have expanded the evolutionary legacy of unicellular ancestors in blood cells. [PDF]

Proc Natl Acad Sci U S A
Nagahata Y, Nishimura Y, Kaitani R, Leong JCK, Oda-Ishii I, Kohtsuka H, Abe S, Ishida T, Carmona-Rivas M, Najle SR, Casacuberta E, Ikuta K, Miura T, Ogasawara M, Irie N, Satou Y, Ruiz-Trillo I, Kawamoto H.   +17 more
europepmc   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Investigation of the protective effects of hydroxytyrosol on erythrocyte deformability during hind limb ischemia-reperfusion injury in rats. [PDF]

Ulus Travma Acil Cerrahi Derg
Kartal H, Kaymak Ş, Şenocak R, Demirdaş E, Demirkıran T, Özdem T, Erol G, Çomu FM, Yavuz B, Ertaş E, Özdaş ME, Özdaş I, Yildirim AK, Tokgoz Y, Ozdemir VC.   +14 more
europepmc   +1 more source

NAT10‐Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment

Advanced Science, EarlyView.
NAT10‐dependent acetylation of circANKRD12 drives translation of the circANKRD12_354aa protein, which binds HDAC2 to stabilize c‐Myc via deubiquitination, promoting multiple myeloma (MM) cell proliferation. Concurrently, the circANKRD12‐HDAC2 axis suppresses H3ac‐mediated transcription of IFN‐γ, TNF‐α, and GZMB in NK cells, leading to NK cell ...
Jiale Zhang, Hui Shi, Chen Wang, Zihao Liu, Lianxin Zhou, Xinyu Lv, Mengjie Guo, Ye Yang, Chunyan Gu   +8 more
wiley   +1 more source

Erratum for the Research Article "A splenic-targeted versatile antigen courier: iPSC wrapped in coalescent erythrocyte-liposome as tumor nanovaccine" by Y. Zhai <i>et al</i>.

Sci Adv
europepmc   +1 more source

Case Report: Abnormally low hemoglobin A1c in a diabetic patient with <i>SLC4A1</i> gene mutation. [PDF]

Front Endocrinol (Lausanne)
Ye L, Ren Q, Ba T, Wu J, Han X, Ji L.
europepmc   +1 more source

Combining Radiation‐Treated Tumor Vaccines With Mn‐MOF Nanoadjuvants to Amplify Radiation Induced Anti‐Tumor Immune Responses

Advanced Science, EarlyView.
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang, Qiqi Qi, Dezhong Li, Jingshi Tang, Weifeng Wang, Zushun Xu, Qi Xu, Fangfang Du, Qianyuan He   +8 more
wiley   +1 more source

Evaluation of the impact of malaria and erythrocyte G6PD deficiency on anaemia outcomes among children in Jos Northcentral Nigeria. [PDF]

BMC Res Notes
Okoli CA, Wamu DI, Deffi F, Leshak PD.
europepmc   +1 more source