Results 51 to 60 of about 24,011 (296)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Plasma viscosity pattern and erythrocyte aggregation in two patients with congenital afibrinogenemia

, 2020
In this case report, we examine the behavior of plasma viscosity, explored at high and low shear rates, and erythrocyte aggregation in two patients with congenital afibrinogenemia, a clinical disorder firstly described in 1920 and that has an estimated ...
Gregorio Caimi, Caimi, Gregorio, Mariasanta Napolitano, Simona Raso, Lo Presti, Rosalia, Raso, Simona, Napolitano, Mariasanta, Rosalia Lo Presti, Siragusa, Sergio, Sergio Siragusa   +9 more
core   +1 more source

THE EFFECT OF AN ANTI-TUMOR NECROSIS FACTOR-? AGENT ON DISEASE ACTIVITY,BLOOD RHEOLOGICAL PROPERTIES, AND THE ARTERIAL WALL IN PSORIATIC ARTHRITIS

Научно-практическая ревматология, 2010
Vascular dysfunction and inflammation in psoriatic arthritis (PsA) share the same pathogenetic mechanism wherein the proinflammatory cytokine tumor necrosis factor-ƒ (TNF-ƒ) plays a key role.
Tatiana Viktorovna Korotaeva, E Yu Loginova, D S Novikova, L N Denisov, E S Mach, N V Klimova, A A Novikov, Sh F Erdes, N N Firsov   +8 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Blood rheological properties and methods of their measurement

Annales Academiae Medicae Silesiensis
From the physical point of view, blood is a multi-phase and multi-component system; plasma is the dispersion medium and the morphotic elements are the dispersed phase.
Tomasz Pryzwan, Patrycja Dolibog, Klaudia Kierszniok, Barbara Pietrzyk   +3 more
doaj   +1 more source

Hemorheology and hemostasis in ischemic stroke patients treated with i.v. thrombolysis

Анналы клинической и экспериментальной неврологии, 2017
Hemostatic and hemorheological dysregulations are the typicalpathological conditions in stroke. Thorough dynamic examinationsof hemostasis, platelet aggregation, kinetics of erythrocyteaggregation/disaggregation along with clinical and ...
M. E. Gafarova, M. A. Domashenko, D. Z. Korobkova, M. Yu. Maximova, M. A. Loskutnikov, A. A. Shabalina, M. V. Kostyreva, R. N. Konovalov   +7 more
doaj   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Acute isovolemic hemodilution triggers proinflammatory and procoagulatory endothelial activation in vital organs: role of erythrocyte aggregation.

, 2006
OBJECTIVES: The essential role of erythrocytes as oxygen carriers is historically well established, but their function to aggregate and the consequences on the microcirculation is under debate.
AURORA M. MORARIU, Morariu, AM, HENRI G. D. LEUVENINK, SIGRIDUR A. ASGEIRSDOTTIR, Leuvenink, Henri G. D.; id_orcid, Leuvenink, Henri G. D., RUTGER J. PLOEG, Maathuis, MH, WIM VAN OEVEREN, GERHARD RAKHORST, Van Oeveren, Wim, INGRID MOLEMA, Rakhorst, G, Leuvenink, HG, Ploeg, RJ, Boonstra, Piet W., Ploeg, Rutger, Boonstra, PW, Asgeirsdottir, SA, van Oeveren, W, MARK‐HUGO J. MAATHUIS, Asgeirsdottir, Sigridur A., Molema, I, PIET W. BOONSTRA, Rakhorst, Gerhard, Morariu, Aurora M., Maathuis, Mark-Hugo J., Molema, Ingrid, Ploeg, Rutger J.   +28 more
core   +1 more source

Erythrocyte sedimentation: Effect of aggregation energy on gel structure during collapse

, 2021
The erythrocyte (or red blood cell) sedimentation rate (ESR) is commonly interpreted as a measure of cell aggregation and as a biomarker of inflammation.
Darras, Alexis, John, Thomas, Gerhard, Gompper, Wagner, Christian, Fedosov, Dmitry A., Gompper, Gerhard, Dasanna, Anil Kumar, Kaestner, Lars   +7 more
core   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source