Results 211 to 220 of about 46,095 (333)

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang   +14 more
wiley   +1 more source

Hematological and biochemical parameters in hereditary spherocytosis under oxidative stress [PDF]

, 1999
Barbot, José, Costa, Elísio, Granjo, Elisa, Nóvoa, Ana, Quintanilha, Alexandre, Rebelo, Irene, Ribeiro, Leticia, Santos-Silva, Alice   +7 more
core   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Influence of erythrocyte density on aggregability as a marker of cell age: Dissociation dynamics in extensional flow [PDF]

Midhun Puthumana Melepattu, Guillaume Maîtrejean, Christian Wagner, Thomas Podgorski   +3 more
openalex   +1 more source

Processing of mitochondrial precursor proteins [PDF]

, 1984
Neupert, Walter, Schmidt, Bernd
core  

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Selenium intake is associated with gait speed in very old adults. [PDF]

Front Aging
Rocha CDN, Henriques GS, Vasconcelos KA, Machado LF, Bicalho MAC, Dos Santos RR, Jansen AK.   +6 more
europepmc   +1 more source

Physiological Reaction of Erythrocytes’ Microrheological Properties on Hypodynamia in Persons of the Second Mature Age

, 2017
N.V. Vorobyeva
openalex   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Erythrocytes as a Source of Exerkines. [PDF]

Int J Mol Sci
Misiti F, Falese L, Iannaccone A, Diotaiuti P.   +3 more
europepmc   +1 more source