Measuring vertebrate telomeres: applications and limitations [PDF]
, 2004 Telomeres are short tandem repeated sequences of DNA found at the ends of eukaryotic chromosomes that function in stabilizing chromosomal end integrity.
Allsopp RC +27 more
core +1 more source
Changes in the Conformational State of Hemoglobin in Hemodialysed Patients with Chronic Renal Failure [PDF]
, 2015 The aim of this study was to evaluate the properties of internal components of erythrocytes in chronic renal failure (CRF) patients undergoing hemodialysis (HD) in comparison to control subjects.
Gwozdzinski, Krzysztof +1 more
core +4 more sources
Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. [PDF]
, 2019 ObjectiveMicroglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca2+-activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing ...
Bushong, Trevor +8 more
core +2 more sources
Early-life adversity accelerates cellular ageing and affects adult inflammation: experimental evidence from the European starling [PDF]
, 2017 Early-life adversity is associated with accelerated cellular ageing during development and increased inflammation during adulthood. However, human studies can only establish correlation, not causation, and existing experimental animal approaches alter ...
Andrews, Clare +8 more
core +4 more sources
Influence of Dietary Capsaicin on Redox Status in Red Blood Cells During Human Aging [PDF]
Advanced Pharmaceutical Bulletin, 2015 Purpose: Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is a major pungent compound found in hot peppers of the plant genus Capsicum. In vitro effects of dietary capsaicin on redox status in red blood cells during human aging have been explored.
Prabhanshu Kumar +3 more
doaj +1 more source
Incidence and predisposing factors of cognitive disorders following off-pump coronary artery bypasses graft surgery [PDF]
, 2014 Patients and Methods: A total of 171 patients who had undergone off-pump CABG without any history of psychiatric disorders were enrolled. Samples were selected according to a purposive sampling method.
Fathi, M. +6 more
core +1 more source
The impact of low erythrocyte density in human blood on the fitness and energetic reserves of the African malaria vector Anopheles gambiae [PDF]
, 2013 Background Anaemia is a common health problem in the developing world. This condition is characterized by a reduction in erythrocyte density, primarily from malnutrition and/or infectious diseases such as malaria.
A Dao +54 more
core +3 more sources
Aging and Clearance of Erythrocytes [PDF]
Transfusion Medicine and Hemotherapy, 2012 As an intro, Beatrix Grubeck-Loebenstein [1] in her function as honorary editor to ‘Experimental Gerontology’ and Director of the Institute for Biomedical Aging Research, in Innsbruck, Austria, describes the topic of aging research in general. She teaches the correct wording and details the various research approaches in this field. Storage lesions,
openaire +2 more sources
Worse Health Status and Higher Incidence of Health Disorders in Rhesus Negative Subjects. [PDF]
PLoS ONE, 2015 Rhesus-positive and Rhesus-negative persons differ in the presence-absence of highly immunogenic RhD protein on the erythrocyte membrane. The biological function of the RhD molecule is unknown.
Jaroslav Flegr +2 more
doaj +1 more source
Contribution of plasma membrane lipid domains to red blood cell (re)shaping
Scientific Reports, 2017 Although lipid domains have been evidenced in several living cell plasma membranes, their roles remain largely unclear. We here investigated whether they could contribute to function-associated cell (re)shaping.
C. Leonard +9 more
doaj +1 more source