Results 301 to 310 of about 46,095 (333)
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Erythrocyte behavior in free-flow electrophoresis is independent of erythrocyte age

Mechanisms of Ageing and Development, 1993
Enzyme activities (acetylcholinesterase, fluorescein diacetate hydrolase, superoxide dismutase), membrane protein band 4.1a/4.1b ratio and density of various fractions of rabbit erythrocytes separated did not show differences between various fractions of erythrocytes separated by free-flow electrophoresis.
G, Bartosz, J, Guclu, P, Soudain
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Polyphosphoinositide metabolism in aging human erythrocytes

Canadian Journal of Biochemistry and Cell Biology, 1985
Normal human erythrocytes were fractionated in a density gradient. Capacity to metabolize polyphosphoinositides was compared in young (least dense) and old (most dense) cells. Polyphosphoinositide synthesis was assessed by following the incorporation of radioactivity from [γ-32P]ATP into the 1-(3-sn-phosphatidyl)-D-myo-inositol 4-phosphate (PtdIns4P ...
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Erythrocyte aging in neurodegenerative disorders.

Cellular and molecular biology (Noisy-le-Grand, France), 2004
In the present paper, we have reviewed the principal studies on red cell membrane abnormalities associated with neurodegenerative disorders. In the literature, two lines of investigation may be recognized: one based on the hypothesis of the presence of an oxidative environment responsible for red cell oxidative damage in Alzheimer's disease (AD ...
DE FRANCESCHI, Lucia   +2 more
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Methotrexate pharmacokinetics in age-fractionated erythrocytes

Cancer Chemotherapy and Pharmacology, 1986
Age fractionation of erythrocytes is useful for further studies of the pharmacokinetics of methotrexate (MTX) in red blood cells. We separated erythrocytes from five blood donors and four patients at different time points after MTX infusions, using discontinuous Percoll gradients consisting of four solutions with a difference of 3% in density among ...
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Erythrocyte aging and malaria.

Cellular and molecular biology (Noisy-le-Grand, France), 2004
The human malaria parasite, Plasmodium falciparum, ages the red blood cell during its intracellular development. During this process of erythrocyte senescence the parasitized cell becomes less dense and deformable, its biconcave disc shape becomes more spherical and is covered with microscopic protuberances (knobs); the amounts of membrane cholesterol ...
I W, Sherman, S, Eda, E, Winograd
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Erythrocyte membrane phosphorylation in aging rats

American Journal of Hematology, 1985
AbstractBy sodium dodecyl sulfate‐polyacrylamide gel electrophoresis (SDS‐PAGE), the protein profile and autophosphorylation of plasma membranes of red cells from 3‐, 9‐, 18‐, and 30‐month‐old rats was examined. No major changes in SDS‐PAGE protein profiles were noticeable.
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Erythrocyte membrane elasticity during in vivo ageing

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1981
Changes in the ability of senescent erythrocytes to pass through the microcirculation may cause them to be trapped in the spleen and removed from the blood. To help understand this process we have measured erythrocyte membrane elasticity, to see whether it changes during in vivo ageing.
G B, Nash, S J, Wyard
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Chapter 3 Erythrocyte Aging

1996
Publisher Summary This chapter discusses erythrocyte aging and the factors responsible for it. The mammalian erythrocyte is a unique model for the study of aging at the cellular and molecular levels, partly because it is devoid of organelles and incapable of protein synthesis.
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