Results 41 to 50 of about 46,095 (333)

Tuning of Differential Lipid Order Between Submicrometric Domains and Surrounding Membrane Upon Erythrocyte Reshaping

Cellular Physiology and Biochemistry, 2018
Background/Aims: Transient nanometric cholesterol- and sphingolipid-enriched domains, called rafts, are characterized by higher lipid order as compared to surrounding lipids.
Catherine Leonard, Hélène Pollet, Christiane Vermylen, Nir Gov, Donatienne Tyteca, Marie-Paule Mingeot-Leclercq   +5 more
doaj   +1 more source

Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias. [PDF]

PLoS ONE, 2016
Aging within the human hematopoietic system associates with various deficiencies and disease states, including anemia, myeloid neoplasms and reduced adaptive immune responses.
Alexandra Rundberg Nilsson, Shamit Soneji, Sofia Adolfsson, David Bryder, Cornelis Jan Pronk   +4 more
doaj   +1 more source

Alkaline Water and Longevity: A Murine Study [PDF]

, 2016
The biological effect of alkaline water consumption is object of controversy. The present paper presents a 3-year survival study on a population of 150 mice, and the data were analyzed with accelerated failure time (AFT) model.
Baratella, Davide, Bonaiuto, Emanuela, Corain, Livio, Corraducci, Vittorino, Ferro, Silvia, Magro, Massimiliano, Salmaso, Luigi, Terzo, Milo, Vianello, Fabio   +8 more
core   +3 more sources

Effects of zinc supplementation on cognitive function in healthy middle-aged and older adults: the ZENITH study [PDF]

, 2006
A randomised double-blind placebo-controlled design was employed to investigate the effects of Zn supplementation on cognitive function in 387 healthy adults aged 55–87 years. Several measures of visual memory, working memory, attention and reaction time
Andriollo-Sanchez, Maud, Coudray , Charles, Maylor, Elizabeth A., McConville, C. F. (Chris F.), Meunier, Nathalie, O'Connor, Jacqueline M., Polito, Angela, Secker, David L., Simpson, Ellen E. A., Stewart-Knox, Barbara   +9 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Erythrocyte Senescence in a Model of Rat Displaying Hutchinson-Gilford Progeria Syndrome

Analytical Cellular Pathology, 2018
Background. Increased oxidative stress is a major cause of aging and age-related diseases. Erythrocytes serve as good model for aging studies. Dihydrotachysterol is known to induce premature aging feature in rats mimicking Hutchinson-Gilford progeria ...
Manoj Kumar Chaudhary, Syed Ibrahim Rizvi   +1 more
doaj   +1 more source

Separation of Erythrocytes of Different Ages

Clinical Chemistry, 1965
Abstract Several methods have been evaluated for the separation of red cells of different ages on the basis of density differences. Simple sedimentation and flotation technics have been found to be unsatisfactory. Centrifugation, followed by a modified sampling procedure, has been demonstrated to provide excellent separation of ...
D J, O'CONNELL, C J, CARUSO, M D, SASS
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Erythrocytes, a New Contributor to Age‐Associated Loss of Blood–Brain Barrier Integrity

Advanced Science, 2021
Blood exchanges between young and old partners demonstrate old blood has a detrimental effect on brain health of young animals. Previous studies primarily investigate soluble blood factors, such as transforming growth factor‐beta, on the brain and the ...
Payam Amiri, Jonalyn DeCastro, Joshua Littig, Hsiang‐Wei Lu, Chao Liu, Irina Conboy, Kiana Aran   +6 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source