Results 91 to 100 of about 24,129 (300)

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Some Blood Parameters in Sea Bass (Dicentrarchus labrax L) Wıth Respect to Water Quality Parameters

Journal of Agricultural Sciences, 1999
ThiS study was conducted to determine the seasonal values of some b]ood parameters (hernat':" hemoglobin, the numbers of erythrocyte, leucocyte and trombocyte as we|l as Wintrobe erythrocyte indices) in c]lı :, healthy sea bass reared at a commercial ...
Hijran Yavuzcan
doaj  

Anemia and Erythrocyte Indices Are Associated With Neurocognitive Performance Across Multiple Ability Domains in Adults With HIV. [PDF]

J Acquir Immune Defic Syndr, 2023
Okwuegbuna OK, Kaur H, Jennifer I, Bush WS, Bharti A, Umlauf A, Ellis RJ, Franklin DR, Heaton RK, McCutchan JA, Kallianpur AR, Letendre SL.   +11 more
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

The effect of anaemia and abnormalities of erythrocyte indices on HbA1c analysis: a systematic review

, 2015
Aims/hypothesis: The use of HbA1c for the diagnosis of diabetes is now widely advocated despite caveats to its use. Anaemia is cited as a major confounder to this use; however, the effect of erythrocyte indices and to what degree anaemia influences HbA1c
Smith, Georgina, Dhatariya, Ketan, Kilpatrick, Eric S, Idris, Iskandar, John, W. Garry, English, Emma   +5 more
core   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Red cell distribution width-to-platelet count ratio is a promising predictor of functional bowel disease

Family Medicine & Primary Care Review, 2022
Gizem Kahveci, Gulali Aktas, Burcin Atak Tel, Satilmis Bilgin, Ozge Kurtkulagi, Buse Balci, Asli Erturk, Tuba Duman   +7 more
doaj   +1 more source

Effects of embryonic cadmium exposure on erythrocyte indices and morphology in newly hatched Gallus gallus domesticus chicks. [PDF]

Poult Sci, 2022
Bojarski B, Chmurska-Gąsowska M, Gałuszka A, Kozłowska A, Kotula-Balak M, Trela M, Kirpaniova A, Kustra K, Stonawski B, Łapiński S, Arent Z, Lis MW.   +11 more
europepmc   +1 more source

Erythrocyte indices in the second trimester of pregnancy: are reference values well established?

The erythrocyte index values in the pregnancy-puerperal cycle behave in a particular manner, however, the physiological or nosological meaning of such alterations are not well established. This study was aimed at analyzing the distribution of erythrocyte
Cristiane C. Bresani, Malaquias Batista Filho, Ariani I. Souza   +2 more
core   +1 more source