Results 71 to 80 of about 24,129 (300)

Erythrocyte Indices for Beta-thalassemia Trait (BTT) Screening in Indonesia: A Scoping Review

open access: yes
Background: Thalassemia is a monogenic disorder that ranks fifth among the catastrophic diseases in Indonesia. Thalassemia screening plays an important role in preventing the birth of individuals with thalassemia major.
Nugraha, Widya Eka   +4 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

open access: yesAdvanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang   +16 more
wiley   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang   +11 more
wiley   +1 more source

The Red Blood Cell Membrane of Preterm Infants in the Early Neonatal Period

open access: yesОбщая реаниматология, 2014
Objective: to study the nanostructure of red blood cell membranes and erythrocyte index in preterm neonatal infants.Subjects and methods. The trial enrolled 47 neonatal infants, including 33 preterm infants who were included in a study group and 14 ...
S. A. Perepelitsa   +2 more
doaj   +1 more source

Serum ferritin and erythrocyte indices in iron overload.

open access: yesBlood transfusion = Trasfusione del sangue, 2007
Raised levels of serum transferrin saturation (TS) and ferritin (SF) are frequently associated with increased values of haemoglobin and erythrocyte indices. In hereditary haemochromatosis this phenomenon has been considered to be a beneficial effect of the C282Y mutation, protecting women from iron deficiency.
openaire   +2 more sources

Impact of smoking on erythrocyte indices and oxidative stress in acute myocardial infarction

open access: yes, 2015
Context: The free radicals generated by cigarette smoke are responsible for the production of excessive oxidative stress, causing damage to the cellular and subcellular components in acute myocardial infarction (AMI).
Saiprasad S Gunti   +4 more
core   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

open access: yesAdvanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu   +9 more
wiley   +1 more source

The Changes of Erythrocyte Indices in Pesticide Factory Workers

open access: yesMedical Laboratory Journal, 2008
Background and Objectives: Erythrocyte indices are helpful for monitoring the erythrocyte synthesis and liver condition. The pesticide factories’ staff are being exposed to poisoning.
HR Joshaghani, KH Kalavi, N Namjoo
doaj  

Assessment of the functional state of the body of highly qualified swimmers based on the analysis of correlations and dynamics of indicators of the morphological composition of the blood after the stress test

open access: yesСпортивная медицина: наука и практика
Objective: to evaluate the interactions and dynamics of hematological parameters before and after exercise testing in high performance sprint swimmers.Materials and methods: 16 male (n = 8) and female (n = 8) high‑performance swimmers (19.31 ± 1.08 years)
A. Z. Dautova   +4 more
doaj   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

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