Results 171 to 180 of about 42,293 (332)
Abstract Background Screening blood donations for HEV RNA mitigates the risk of transfusion‐transmitted HEV infection (TT‐HEV), a recognised blood safety issue in Europe. This study reports the findings of government‐funded HEV RNA blood donation screening 2016–2022 and includes an estimate of residual risk. Method Donation samples were universally and
Niamh O'Flaherty +6 more
wiley +1 more source
Abstract Background Blood transfusion remains a cornerstone in the management of sickle cell disease (SCD); however, it is frequently complicated by red cell alloimmunisation. A significant debate persists within the scientific community regarding the optimal strategy to mitigate this risk: the traditional, pragmatic approach of serologic phenotyping ...
Christiane Ruffato Carminati +6 more
wiley +1 more source
Development of molecular sterility assay for rapid quality release of cord blood erythrocytes units for transfusion [PDF]
Laia Closa +10 more
openalex +1 more source
Clinical implications of imlifidase interference in antibody screening and transfusion management
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani +2 more
wiley +1 more source
The Effect of Transfusions of Erythrocytes on Untreated Pernicious Anemia [PDF]
JAMES D. MASON, Byrd S. Leavell
openalex +1 more source
Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike +33 more
wiley +1 more source
Abstract Background Extremely preterm neonates often require red blood cell (RBC) transfusions derived from adult donors. These transfusions introduce adult hemoglobin into a neonatal hematopoietic system dominated by fetal hemoglobin (HbF), shifting the oxygen‐dissociation curve and increasing oxygen delivery to immature tissues.
Jip H. van Daelen +8 more
wiley +1 more source
Abstract Background Cryoprecipitate Anti‐Haemophilic Factor (CRYO‐AHF) is enriched for fibrinogen, VWF, FVIII, FXIII and fibronectin, but has short post‐thaw expiration due to risk of transfusion‐transmitted infection (TTI) limiting availability for rapid treatment.
Florian Tupin +6 more
wiley +1 more source
Transfusion strategies in thalassemia and sickle cell disease SITE-SIMTI-SIdEM Good Practice. [PDF]
Forni GL +8 more
europepmc +1 more source

