Results 91 to 100 of about 479,495 (370)
A Plant-Like Kinase in Plasmodium falciparum Regulates Parasite Egress from Erythrocytes
It's a Knockout The malaria parasite is one of the most important pathogens of humans. Increasing drug-resistance is an imminent public health disaster, and we urgently need to find new drugs.
Jeffrey D. Dvorin+12 more
semanticscholar +1 more source
Objective Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA. Methods We included patients with PsA followed at our prospective observational cohort for the period between 1978 ...
Fadi Kharouf+6 more
wiley +1 more source
Effects of hemodialysis on blood fatty acids
Omega‐3 (n‐3) fatty acids have beneficial cardiovascular effects, perhaps also in chronic kidney disease (CKD) patients. A low omega‐3 index is an independent cardiovascular risk factor in end‐stage renal disease (ESRD) dialysis patients.
Benjamin Gollasch+4 more
doaj +1 more source
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu+6 more
wiley +1 more source
Platelet Inhibition by Nitrite Is Dependent on Erythrocytes and Deoxygenation
Background Nitrite is a nitric oxide (NO) metabolite in tissues and blood, which can be converted to NO under hypoxia to facilitate tissue perfusion. Although nitrite is known to cause vasodilation following its reduction to NO, the effect of nitrite on ...
Sirada Srihirun+9 more
semanticscholar +1 more source
The chicken erythrocyte epigenome [PDF]
Transcriptional regulation is impacted by multiple layers of genome organization. A general feature of transcriptionally active chromatin is sensitivity to DNase I and association with acetylated histones. However, very few of these active DNase I-sensitive domains, such as the chicken erythrocyte β-globin domain, have been identified and characterized.
Jahan, Sanzida+5 more
openaire +2 more sources
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan+4 more
wiley +1 more source
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García+23 more
wiley +1 more source
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai+9 more
wiley +1 more source
Introduction. Zygophyllum album (Z. album) is used in traditional medicine for a long time for its anti-diabetic activities. Objective. To investigate Z.
Yasmina BAHLIL+2 more
doaj +1 more source