Results 211 to 220 of about 241,660 (316)

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

Microfluidic platform for automatic quantification of malaria parasite invasion under physiological flow conditions.

Lab Chip
Kals E, Kals M, Introini V, Vodenicharski B, Kotar J, Rayner JC, Cicuta P.   +6 more
europepmc   +1 more source

Evaluation of the genotoxic, antigenotoxic and teratogenic effects of water-based Turkish propolis, and its chemical composition. [PDF]

RSC Adv
Araba S, Özparlak H, Zengin G.
europepmc   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

Correction to: Mapping the expression of endothelial adhesion receptors for Plasmodium falciparum-infected erythrocytes in fatal cerebral malaria in Malawian children. [PDF]

J Neuropathol Exp Neurol
europepmc   +1 more source

Zinc ions attenuates iridovirus infection through regulation of ferroptosis pathways. [PDF]

Cell Death Discov
You Y, Liang M, Cao X, Pan W, He J, Wu K, Weng S, He J, Guo C.   +8 more
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Erythropoiesis-inosine metabolic axis failure underlying retinal neurodegeneration in glaucoma: novel diagnoses and therapies. [PDF]

Exp Mol Med
Chou Y, Liu W, Li Y, Chen C, Luo C, Shen S, Dai P, Feng L, Xiao W, Wang Y, Wang J, Wan L, Yang Z, Xie T, Zhang Y, Kellems RE, Song W, Xia X, Xia Y.   +18 more
europepmc   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, EarlyView.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Application of <i>In Vivo</i> Cryotechnique for Morphological Visualization of Nerve and Vascular Structures in a Sciatic Nerve Crush Model. [PDF]

Acta Histochem Cytochem
Fukuda K, Sakamoto Y, Shimo S, Amari T, Takasu C, Kubota K, Murata K, Kanemura N.   +7 more
europepmc   +1 more source