Results 211 to 220 of about 375,002 (307)

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

Immune functions of avian erythrocytes: a comprehensive review from basic biology to pathogen-induced responses. [PDF]

Front Immunol
Cai F, Wang Y.
europepmc   +1 more source

Dysmorphic Erythrocytes to Erythrocytes Ratio Measurement [PDF]

, 2020
openaire   +1 more source

ORIGIN OF ERYTHROCYTES [PDF]

Nature, 1947
openaire   +2 more sources

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

Advanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi, Zhengcao Xing, Libo Luo, Jiale Wang, Xinyu Liu, Jia Yu, Jizhong Yin, Bin Chen, Yiwei Liu, Hui Sun, Guanghui Gao, Lei Wang, Xiaoxia Chen, Fei Li, Hu Ma, Lin Wang, Shuo Yang, Shengxiang Ren   +17 more
wiley   +1 more source

Structure-Dependent Antioxidant Activity of Ibogalogs: Impact of Methoxy Group Position on the Protective Activity in Model and Synaptosomal Lipid Membranes. [PDF]

ACS Chem Neurosci
Kazmierska-Grebowska P, Grebowski J, Żebrowski M, DiLabio GA, Ciesielski O, Balcerczyk A, Arias HR, Litwinienko G.   +7 more
europepmc   +1 more source

Self‐Nitriding Nanostructured Transition Metal Nitrides in Architected‐Carbon Matrices: Unveiling Mechanisms and Advancing Performance in Lithium‐Sulfur Pouch Cells

Advanced Science, EarlyView.
Imidazolium PIL nanoparticles, as an N‐rich template and morphology director, enable a colloidal self‐nitriding route to TMNs (VN, Mo2N) within controlled solid/hollow carbon architectures. As sulfur hosts/additives, TMNs accelerate Li–S redox kinetics and support high‐loading cathodes.
Yael Rodriguez Ayllon, Liqiang Lu, Dongjiu Xie, Xuefeng Pan, Teodor Jianu, Fangmu Qu, Sijia Cao, Yu Zhang, Roberto Félix, Marcus Bär, Nadezda V. Tarakina, Johannes Schmidt, Qingping Wu, Jiayin Yuan, Yan Lu   +14 more
wiley   +1 more source

In vivo mammalian micronucleus test in mice confirms lack of genotoxic potential of a protein-rich powder derived from Xanthobacter sp. SoF1. [PDF]

Genes Environ
Choi B, Endres JR, Clewell A, Hirka G, Béres E.   +4 more
europepmc   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

Stomatin encapsulates aquaporin-1 and urea transporter-B in the erythrocyte membrane. [PDF]

Sci Adv
Vallese F, Li H, Barazzuol L, Calì T, Clarke OB.   +4 more
europepmc   +1 more source