Results 221 to 230 of about 479,495 (370)

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

Advanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu, Xing‐Yue Zhou, Da‐Lian Qin, Qan Qiao, Qiao‐Zhi Wang, Shi‐Ying Li, Yun‐Fei Zhu, Ya‐Ping Li, Jiang‐Min Zhou, Hui Cai, Fei‐Hong Huang, Lu Yu, Long Wang, An‐Guo Wu, Jian‐Ming Wu, Xiao‐Gang Zhou   +15 more
wiley   +1 more source

Deep learning image analysis for continuous single-cell imaging of dynamic processes in Plasmodium falciparum-infected erythrocytes. [PDF]

Commun Biol
Frangos SM, Damrich S, Gueiber D, Sanchez CP, Wiedemann P, Schwarz US, Hamprecht FA, Lanzer M.   +7 more
europepmc   +1 more source

Enzymes in cancer. The β-glycerophosphatase of the erythrocytes [PDF]

, 1935
Janetta Wright Schoonover, J.O. Ely
openalex   +1 more source

Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts

Advanced Science, EarlyView.
Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast‐spiking interneurons exhibit reduced excitability, whereas regular‐spiking neurons showed increased bursting activity. Disruptions in low‐gamma phase locking suggest persistent
Yifu Jin, Fei He, Haad Rathore, Yingchu Sun, Jia‐ao Zhang, Xinyu Li, Rongkang Yin, Hanlin Zhu, Chong Xie, Lan Luan   +9 more
wiley   +1 more source

Initiation of Progressive Morphological Transition Towards an Echino-Stomato-Spherocytic Phenotype by Phosphatidylserine Externalization and Its Implication in Thrombosis. [PDF]

Int J Mol Sci
Bian Y, Jin Q, Chung HY, Lim KM, Xu Y.
europepmc   +1 more source

Plac1+ Tumor Cell‐Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer

Advanced Science, EarlyView.
Meng et al. screen genes in the CTAs family and find Plac1 is specifically expressed in head and neck squamous cell carcinoma (HNSCC) cells. They reveal that Plac1 expression promotes HNSCC progression directly by activating PI3K/AKT signaling pathway.
Xiaoyan Meng, Zhonglong Liu, Lu Zhao, Ran Li, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He   +8 more
wiley   +1 more source

Oligomer assembly of <i>Bacillus thuringiensis</i> Cyt2Aa2 on lipid membranes reveals a thread-like structure. [PDF]

Toxicon X
Tangsongcharoen C, Toca-Herrera JL, Promdonkoy B, Srisucharitpanit K, Tharad S.   +4 more
europepmc   +1 more source

MECHANISMS CONTROLLING CATION CONCENTRATIONS IN THE HUMAN CELL: EVIDENCE FROM THE EFFECT OF IODOACETATE ON Na AND K EXCHANGE RATES OF THE ERYTHROCYTE 1 [PDF]

, 1955
William D. Love, J. A. CRONVICH, G.E. Burch   +2 more
openalex   +1 more source

Targeting PFKFB4 Biomimetic Codelivery System Synergistically Enhances Ferroptosis to Suppress Small Cell Lung Cancer and Augments the Efficacy of Anti‐PD‐L1 Immunotherapy

Advanced Science, EarlyView.
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu, Jingjun He, Haoxuan Ying, Cuiying Chen, Chongyang Zheng, Peng Luo, Weiliang Zhu, Ting Wei, Bufu Tang, Jian Zhang   +9 more
wiley   +1 more source

Accessible ecophysiological tools for seabird conservation

Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 32, Issue 12, Page 1983-2002, December 2022., 2022
Abstract Seabirds are the most endangered avian taxa on Earth, with over a third of species globally threatened. To help slow their decline, conservation physiology seeks to determine how seabird responses to climatic and anthropogenic threats influence demographic processes, but it is not widely utilized in monitoring.
Edin A. Whitehead, Brendon J. Dunphy
wiley   +1 more source