Results 231 to 240 of about 495,043 (357)

Potential Therapeutic Targets and Emerging Strategies to Promote Hematoma Resolution in Intracerebral Hemorrhage. [PDF]

Rev Neurol
Wan S, Ji X, Meng R, Li M.
europepmc   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Generation of Enucleated Erythrocytes From Lin^-CD45^-CD133⁺ Cells Isolated From Human Umbilical Cord Blood In Vitro. [PDF]

Stem Cells Int
He J, Wang F, Zhan Q, Sheng Q, Ying Y, Zhang W, Liu J, Zhu F.   +7 more
europepmc   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

Biophysical and structural modifications on human erythrocytes induced by ethanolic extracts of <i>Ruta graveolens</i>, <i>Artemisia ludoviciana</i>, and <i>Lippia graveolens</i>: a study by ATR-FTIR spectroscopy. [PDF]

RSC Adv
de la O-Cuevas E, Gallegos-Flores P, Ortega-Sigala JJ, Tototzintle-Huitle H, Saniger JM, Esparza-Ibarra EL.   +5 more
europepmc   +1 more source

Obesidad y su relación con marcadores de inflamación y ácidos grasos de eritrocito en un grupo de adolescentes obesos Obesity and its relation with markers of inflammation and erythrocyte fatty acids in a group of overweight adolescents

, 2012
María José Aguilar Cordero, Emilio González‐Jiménez, Javier S. Perona, C. A. Padilla López, J. Álvarez Ferre, E. Ocete Hita, M. Rizo Baeza, Rafael Guisado Barrilao, Francisca Rivas   +8 more
openalex   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

<i>In vivo</i> genotoxicity of Chios mastic gum in rodent bone marrow micronucleus test. [PDF]

Toxicol Rep
Psarou EC, Termentzi A, Kyriakopoulou K, Anastasiadou P, Meidanis M, Fokialakis N, Machera K.   +6 more
europepmc   +1 more source

A simple method for clinical assay of superoxide dismutase.

Clinical Chemistry, 1988
Yi Sun, L. Oberley, Ying Li
semanticscholar   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source