Results 81 to 90 of about 479,495 (370)

Pannexin 1 in erythrocytes: Function without a gap

Proceedings of the National Academy of Sciences of the United States of America, 2006
ATP is a widely used extracellular signaling molecule. The mechanism of ATP release from cells is presently unresolved and may be either vesicular or channel-mediated. Erythrocytes release ATP in response to low oxygen or to shear stress.
S. Locovei, Li Bao, G. Dahl
semanticscholar   +1 more source

Exploring surface‐guided systems for intelligent breathing‐adapted four‐dimensional computed tomography: A comparison to infrared‐based reflective marker systems

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study evaluates the technical feasibility of adapting a surface monitoring system, designed for conventional four‐dimensional computed tomography (4DCT), to an intelligent, breathing‐adapted 4DCT and examines its potential to expand the currently limited range of supported surrogate systems.
Niklas Lackner, Andre Karius, Rainer Fietkau, Christoph Bert, Juliane Szkitsak   +4 more
wiley   +1 more source

Evidence of blood–brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro, Neetha Paul Eduthan, Mellad M. Khoshnood, Saba Jafarpour, Natalie K. Boyd, Benjamin N. Vogel, Lina Nguyen, Lilia Kazerooni, Eleanor Britton, Hannah R. Lyford, Matthew D. Galbraith, Angela L. Rachubinski, Joaquin M. Espinosa   +12 more
wiley   +1 more source

A New Strategy for the Morphological and Colorimetric Recognition of Erythrocytes for the Diagnosis of Forms of Anemia based on Microscopic Color Images of Blood Smears [PDF]

International journal of advanced computer science and applications (IJACSA), 2020, 11 (7), pp.488-497, 2023
The detection of red blood cells based on morphology and colorimetric appearance is very important in improving hematology diagnostics. There are automatons capable of detecting certain forms, but these have limitations with regard to the formal identification of red blood cells because they consider certain cells to be red blood cells when they are ...
arxiv  

Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications

Expert Reviews in Molecular Medicine, 2009
Severe malaria has a high mortality rate (15–20%) despite treatment with effective antimalarial drugs. Adjunctive therapies for severe malaria that target the underlying disease process are therefore urgently required.
J. A. Rowe, A. Claessens, R. Corrigan, M. Arman   +3 more
semanticscholar   +1 more source

Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita, Neel Desai, Abigail R. Manning, Caitlin Pileggi, Sara Manning Peskin, Danielle K. Sandsmark, Dennis L. Kolson, Matthew K. Schindler   +7 more
wiley   +1 more source

The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment.

Blood, 2012
Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by complement-mediated intravascular hemolysis because of the lack from erythrocyte surface of the complement regulators CD55 and CD59, with subsequent uncontrolled continuous spontaneous ...
A. Risitano, R. Notaro, Caterina Pascariello, M. Sica, L. del Vecchio, C. Horvath, M. Fridkis-Hareli, C. Selleri, M. Lindorfer, R. Taylor, L. Luzzatto, V. Holers   +11 more
semanticscholar   +1 more source

Erythrocyte Protoporphyrin [PDF]

Blood, 1972
Abstract Blood protoporphyrin (PROTO) concentration in man and animals has been studied as a possible means of assessing the relationship between iron supply and marrow requirements. There appear to be two fractions of PROTO: one at a level of about 30 µg/ 100 ml unrelated to either iron supply or cell age, and a second fraction that ...
E E, Langer, R G, Haining, R F, Labbe, P, Jacobs, E F, Crosby, C A, Finch   +5 more
openaire   +2 more sources

Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open‐Label, Phase 1 Trial

Arthritis Care &Research, EarlyView.
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner, Anna Shmagel, Gerd Horneff, Ivan Foeldvari, Jordi Antón, Athimalaipet V. Ramanan, Yuli Qian, Kristina Unnebrink, Shuai Hao, Heidi S. Camp, Nasser Khan, Wei Liu, Mohamed‐Eslam F. Mohamed   +12 more
wiley   +1 more source

Three-Dimensional Reconstruction of Erythrocyte in the Capillary [PDF]

arXiv, 2013
The dynamic analysis of erythrocyte deformability is used as an important means for early diagnosis of blood diseases and blood rheology. Yet no effective method is available in terms of three-dimensional reconstruction of erythrocytes in a capillary.
arxiv