Results 61 to 70 of about 241,660 (316)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Erythrocytes enhance oxygen-carrying capacity through self-regulation

Frontiers in Physiology
Once considered passive carriers of oxygen, erythrocytes are now understood to play active roles in regulating oxygen homeostasis and redox balance. This review examines the molecular mechanisms through which red blood cells adapt to hypoxic conditions ...
Ying Xu, Zhangjie Yu, Hanxuan Liu, Xiaohan Bian, Weiliang Tang   +4 more
doaj   +1 more source

Injuries of peripheral blood erythrocytes and microhemocirculation in children with Henoch–Schonlein purpura

Бюллетень сибирской медицины, 2005
Analysis results of pathomorphism of clinical course in 174 children having Henoch–Schonlein purpura (HSP) during a 10-year period (from January 1, 1990 to December 31, 2000) are presented in the paper.
T. A. Nagaeva, I. I. Balasheva, M. N. Bocharova   +2 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

An alternative vaccine target for bovine Anaplasmosis based on enolase, a moonlighting protein

Frontiers in Veterinary Science, 2023
The discovery of new targets for preventing bovine anaplasmosis has moved away from focusing on proteins that have already been extensively studied in Anaplasma marginale, including the Major Surface Proteins, Outer Membrane Proteins, and Type IV ...
Rosa Estela Quiroz-Castañeda, Hugo Aguilar-Díaz, Itzel Amaro-Estrada   +2 more
doaj   +1 more source

On the Shape of the Erythrocyte

Biophysical Journal, 1968
A model is postulated which attributes the distinctive biconcave shape of the human erythrocyte to a balance of forces acting on the membrane. The forces considered are electrostatic forces due to a charge distribution on the membrane, a hydrostatic pressure difference acting across the membrane, and forces arising from a constant tension in the ...
Lopez, L., Duck, I.M., Hunt, W.A.
openaire   +2 more sources

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

In vitro inhibition of Plasmodium falciparum rosette formation by Curdlan sulfate

, 2007
Spontaneous binding of infected erythrocytes to uninfected erythrocytes to form rosettes is a property of some strains of Plasmodium falciparum that is linked to severe complications of malaria.
Steen, Katie E, Bull, PC, Warimwe, G, Arman, M, Raza, Ahmed, Bull, Peter, Havlik, I, Steen, KE, Arman, Monica, Rowe, J Alexandra; id_orcid, Kyriacou, HM, Warimwe, George, Havlik, Ivan, Kyriacou, Helen M, Bull, Peter C, Raza, A, Rowe, JA   +16 more
core   +1 more source

AAPH-induced oxidative damage reduced anion exchanger 1 (SLC4A1/AE1) activity in human red blood cells: protective effect of an anthocyanin-rich extract

Frontiers in Physiology, 2023
Introduction: During their lifespan in the bloodstream, red blood cells (RBCs) are exposed to multiple stressors, including increased oxidative stress, which can affect their morphology and function, thereby contributing to disease.Aim: This ...
Alessia Remigante, Sara Spinelli, Giuseppe Tancredi Patanè, Davide Barreca, Elisabetta Straface, Lucrezia Gambardella, Giuseppina Bozzuto, Daniele Caruso, Giuseppe Falliti, Silvia Dossena, Angela Marino, Rossana Morabito   +11 more
doaj   +1 more source