Results 61 to 70 of about 63,832 (257)

An alternative vaccine target for bovine Anaplasmosis based on enolase, a moonlighting protein

Frontiers in Veterinary Science, 2023
The discovery of new targets for preventing bovine anaplasmosis has moved away from focusing on proteins that have already been extensively studied in Anaplasma marginale, including the Major Surface Proteins, Outer Membrane Proteins, and Type IV ...
Rosa Estela Quiroz-Castañeda, Hugo Aguilar-Díaz, Itzel Amaro-Estrada   +2 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

AAPH-induced oxidative damage reduced anion exchanger 1 (SLC4A1/AE1) activity in human red blood cells: protective effect of an anthocyanin-rich extract

Frontiers in Physiology, 2023
Introduction: During their lifespan in the bloodstream, red blood cells (RBCs) are exposed to multiple stressors, including increased oxidative stress, which can affect their morphology and function, thereby contributing to disease.Aim: This ...
Alessia Remigante, Sara Spinelli, Giuseppe Tancredi Patanè, Davide Barreca, Elisabetta Straface, Lucrezia Gambardella, Giuseppina Bozzuto, Daniele Caruso, Giuseppe Falliti, Silvia Dossena, Angela Marino, Rossana Morabito   +11 more
doaj   +1 more source

Effect of Thioridazine on Erythrocytes [PDF]

Toxins, 2013
Background: Thioridazine, a neuroleptic phenothiazine with antimicrobial efficacy is known to trigger anemia. At least in theory, the anemia could result from stimulation of suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage and by phospholipid scrambling of the cell membrane with phosphatidylserine exposure at the ...
Lang, E., Modicano, P., Arnold, M., Bissinger, R., FAGGIO, Caterina, Abed, M., Lang, F.   +6 more
openaire   +6 more sources

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

Arthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

A mathematical model of fibrinogen-mediated erythrocyte–erythrocyte adhesion

Communications Biology, 2023
AbstractErythrocytes are deformable cells that undergo progressive biophysical and biochemical changes affecting the normal blood flow. Fibrinogen, one of the most abundant plasma proteins, is a primary determinant for changes in haemorheological properties, and a major independent risk factor for cardiovascular diseases.
Catarina S. Lopes, Juliana Curty, Filomena A. Carvalho, A. Hernández-Machado, Koji Kinoshita, Nuno C. Santos, Rui D. M. Travasso   +6 more
openaire   +7 more sources

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure [PDF]

, 2012
Contains fulltext : 107961.pdf (Publisher’s version ) (Open Access)Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Dinkla, S., Brock, R.E., Dinkla, S, Cluitmans, JC, Fuchs, B, Joosten, I, Fransen, J., Tomelleri, C, Verdurmen, W.P.R., Bosman, G.J.C.G.M., Wessels, K, Schiller, J., Wessels, K., Brock, R, Fuchs, B., Verdurmen, WP, Joosten, I., Bosman, GJ, Cluitmans, J.C.A., Schiller, J, Tomelleri, C., Fransen, J   +21 more
core   +2 more sources

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Interactions Between Aerolysin, Erythrocytes, and Erythrocyte Membranes [PDF]

Infection and Immunity, 1975
Aerolysin, a hemolytic and lethal exotoxin of Aeromonas hydrophila , was analyzed for amino acids. Assuming 8 histidine residues/mol, the purified toxic protein has, by summation, a molecular weight of 49,000, a value in agreement with earlier estimates by other methods.
A W, Bernheimer, L S, Avigad, G, Avigad
openaire   +2 more sources

RNA-Seq reveals an integrated immune response in nucleated erythrocytes [PDF]

, 2011
Background: Throughout the primary literature and within textbooks, the erythrocyte has been tacitly accepted to have maintained a unique physiological role; namely gas transport and exchange.
Steven Roberts, Balasch, Joan C, Frederick W Goetz, Simon A MacKenzie, Joan Carles Balasch, Nerea Roher, Goetz, Frederick W., Callol, Agnes, Laia Ribas, Boltaña Sebastian, Balasch, Joan Carles, Goetz Frederick W., Balasch Alemany, Joan Carles, Goetz, Frederick W, Morera, Davinia, Roher Nerea, Roberts, Steven, Ribas Cabezas, Laia, Sebastian Boltaña, Roher, Nerea, Agnes Callol, Davinia Morera, Doñate Carmen, Goetz, Giles, Goetz Giles, Boltana, Sebastian, Balasch Joan Carles, Mackenzie, Simon, Frederick W. Goetz, Morera Capdevila, Davinia, Callol Agnes, Ribas, Laia, Roher Armentia, Nerea, Goetz, Frederick William, Doñate Jimeno, Carmen, Roberts Steven, Morera Davinia, Ribas Laia, Donate, Carmen, Simon A. MacKenzie, Giles Goetz, Carmen Doñate, MacKenzie Simon A., Callol Junyer, Agnès   +43 more
core   +1 more source