Results 41 to 50 of about 375,002 (307)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

In Vitro Measurement of the Elastic Properties of the Native Red Blood Cell Membrane

Общая реаниматология, 2015
Objective: to develop a procedure to image native cells in a physiological medium and to measure the local stiffness of fixed red blood cell membranes in liquid in vitro experiments.Material and methods.
V. A. Sergunova, E. K. Kozlova, E. A. Myagkova, A. M. Chernysh   +3 more
doaj   +1 more source

Erythrocyte metabolism

Acta Physiologica
AbstractOur aim is to present an updated overview of the erythrocyte metabolism highlighting its richness and complexity. We have manually collected and connected the available biochemical pathways and integrated them into a functional metabolic map.
Panagiotis N. Chatzinikolaou, Nikos V. Margaritelis, Vassilis Paschalis, Anastasios A. Theodorou, Ioannis S. Vrabas, Antonios Kyparos, Angelo D'Alessandro, Michalis G. Nikolaidis   +7 more
openaire   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Phenotypic features of erythrocytes and activity of erythropoiesis in cardiosurgical patients with various degree of postperfusion hemolysis manifestation

Бюллетень сибирской медицины, 2012
A study of phenotypic characteristics of erythrocytes and indicators of activity of erythropoiesis in cardiosurgical patients with moderated (40 patients) and expressed (18 patients) hemolysis after coronary artery bypass grafting in conditions of ...
V. V. Novitsky, S. P. Chumakova, O. I. Urazova, V. M. Shipulin, O. A. Khokhlov, Yu. V. Kolobovnikova   +5 more
doaj   +1 more source

Effect of blood's velocity on blood resistivity [PDF]

, 1998
Blood resistivity is an important quantity whose value influences the results of various methods used in the study of heart and circulation. In this paper, the relationship between blood resistivity and velocity of blood flow was evaluated and analyzed ...
Ng, SL, Tjin, SC, Xie, T, Yang, QP
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Examining Erythrocytes as Potential Blood Biomarkers for Autism Spectrum Disorder: Their Relationship to Symptom Severity and Adaptive Behavior

Biomedicines
Background: Multiple research teams have documented various abnormalities in erythrocyte properties in children with autism spectrum disorder (ASD) compared with neurotypical individuals.
Tomas Jasenovec, Dominika Radosinska, Ivan Belica, Barbara Raskova, Angelika Puzserova, Norbert Vrbjar, Jana Radosinska   +6 more
doaj   +1 more source

MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN

Педиатрическая фармакология, 2014
Examination of 73 children of 8–12 years of age was conducted in order to study morphological characteristics of erythrocytes at undifferentiated connective tissue dysplasia (UCTD). Scanning electron microscopy revealed significant alterations of surface
D. A. Ponomareva, T. A. Nagayeva, I. I. Balasheva, N. M. Shevtsova   +3 more
doaj   +1 more source

Malaria vaccines 1985-2005: a full circle?

, 2005
Few who were actively engaged in malaria vaccine research 20 years ago (including myself) would have imagined that, in 2005, there would still be a prediction of a 10-20-year horizon before vaccines become part of malaria-control strategies.
Targett, Geoffrey A
core   +1 more source