Results 41 to 50 of about 63,832 (257)

Transcribed var genes associated with placental malaria in Malawian women [PDF]

, 2006
Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-infected erythrocytes isolated from placentas is important for attempts to develop a pregnancy-specific malaria vaccine.
Choong, Ee Ken, Boysen, Katja, Molyneux, Malcolm E, Caragounis, Aphrodite, Duffy, Michael F, Healer, Julie, Rowe, J Alexandra; id_orcid, Rogerson, Stephen J, Noviyanti, Rintis, Brown, Graham V, Kyriacou, Helen M   +10 more
core   +1 more source

Storage-induced changes in erythrocyte membrane proteins promote recognition by autoantibodies [PDF]

, 2012
Contains fulltext : 109602.pdf (Publisher’s version ) (Open Access)Physiological erythrocyte removal is associated with a selective increase in expression of neoantigens on erythrocytes and their vesicles, and subsequent autologous ...
Dinkla, S., Věra M J Novotný, Novotný Věra M. J., Věra M. J. Novotný (144892), Dinkla, S, Joosten, I, Novotný, VM, Sip Dinkla, Giel J C G M Bosman, Bosman, G.J.C.G.M., Irma Joosten, Dinkla Sip, Giel J. C. G. M. Bosman (144896), Novotny, V.M.J., Joosten, I., Joosten Irma, Bosman, GJ, Irma Joosten (27492), Bosman Giel J. C. G. M., Sip Dinkla (144890)   +19 more
core   +3 more sources

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Diseased Erythrocyte Enrichment Based on I-Shaped Pillar DLD Arrays

Micromachines
Enrichment of erythrocytes is a necessary step in the diagnosis of blood diseases. Due to the high deformability and viscosity of erythrocytes, they cannot be regarded as stable point-like solids, so the influence of their deformability on fluid dynamics
Yao Lv, Jiangbo Wu, Yongqing He, Jie Liu, Wenyu Zhang, Zihan Yan   +5 more
doaj   +1 more source

The role of Plasmodium falciparum var genes in malaria in pregnancy [PDF]

, 2004
Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected ...
S. A. Kyes, Rowe, J A; id_orcid, J. A. Rowe, Kyes, S A   +3 more
core   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Anaerobic glycolysis and oxidative stress interrelation in erythrocytes under administration of Cornus mas L. fruit extracts to rats with streptozotocin-induced diabetes mellitus

Біологічні студії
Background. In diabetes mellitus (DM), analysis of changes in the biochemical profile of erythrocytes is the important stage of complex scientific research to clarify the mechanism of action of medicinal products based on plant raw materials.
Anna Moroz, Iryna Brodyak, Alicja Z. Kucharska, Natalia Sybirna   +3 more
doaj   +1 more source

Hemotrophic mycoplasmas induce programmed cell death in red blood cells [PDF]

, 2011
Hemotrophic mycoplasmas (HM) are uncultivable bacteria found on and in the red blood cells (RBCs). The main clinical sign of HM infections is the hemolytic anemia. However, anemia-inducing pathogenesis has not been totally clarified. In this work we used
Groebel, K, Ritzmann, Mathias, Hoelzle, Katharina, Kilchling, T, Mathias Ritzmann, Ritzmann, M, Felder, Kathrin M., Hoelzle, K, Ludwig E. Hoelzle, Schiele, D, Katharina Hoelzle, Heinritzi, K, Daniela Schiele, Kilchling, Tim, Kathrin M. Felder, Tim Kilchling, Karl Heinritzi, Felder, K M, Katrin Groebel, Heinritzi, Karl, Groebel, Katrin, Schiele, Daniela, Hoelzle, Ludwig E, Hoelzle, Ludwig E.   +23 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source