Results 31 to 40 of about 7,152 (164)

Enalaprilat and losartan decrease erythroid precursors frequency in cells from patients with polycythemia vera

Hematology, 2023
Objective: Polycythemia Vera (PV) is a myeloproliferative neoplasm characterized by the overproduction of red blood cells. First-line therapies are directed at lowering hematocrit levels. After the discovery of a mutation in the Janus kinase 2 (JAK2V617F)
Angela Bozza, Martina Bernardi, Daniela Catanzaro, Katia Chieregato, Anna Merlo, Giuseppe Astori   +5 more
doaj   +1 more source

Prognostic Value of Perioperative Anemia in Neurosurgical‐Oncological Treatment of Spinal Metastases

International Journal of Cancer, EarlyView.
High perioperative morbidity in patients undergoing surgery for spinal metastases highlights the need to identify modifiable risk factors, particularly the underexplored role of anemia. This study assessed associations between perioperative hemoglobin levels and complications, recurrence, and mortality in patients treated surgically for spinal ...
Marija Janjic, Logman Khalafov, Juliane Dittmer, Saif‐Eldin Abedellatif, Tim Lampmann, Harun Asoglu, Mohammed Jaber, Haitham Alenezi, Muriel Heimann, Matthias Schneider, Motaz Hamed, Marcus Thudium, Hartmut Vatter, Mohammed Banat   +13 more
wiley   +1 more source

Erythrocytosis due to PHD2 Mutations: A Review of Clinical Presentation, Diagnosis, and Genetics

Case Reports in Hematology, 2016
The association of mutations in the PHD2 protein of the hypoxia-sensing pathway and erythrocytosis has only been established in the last decade. Here we report the case of a novel PHD2 gene mutation in a patient with erythrocytosis and summarize all ...
Rachel Wilson, Nausheen Syed, Prabodh Shah   +2 more
doaj   +1 more source

First Report of Co‐Inheritance of Hemoglobin British Columbia (HBB:c.304G>A) and β‐Thalassemia IVS‐I‐6 (HBB:c.92+6T>C): Clinical Characterization of an Iranian Case

Journal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Hemoglobin British Columbia is a rare high‐oxygen‐affinity β‐globin variant caused by the HBB:c.304G>A substitution. Its detection is exceptionally uncommon, particularly in the Middle East, and may lead to diagnostic pitfalls when relying solely on hemoglobin separation techniques.
Kimia Fathalizade, Mahsa Kiani Bigdeli, Seyed Sajad Eghbali, Mohammadtaghi Ghiyasi, Roz Rastgoo, Mohammad Javad Mousavi   +5 more
wiley   +1 more source

Reference Interval Establishment for Four Coagulation Parameters Using Indirect Methods in a High‐Altitude Chinese Population: A Retrospective Real‐World Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
This study established reference intervals for APTT, PT, TT, and FIB in a Tibetan high‐altitude population using two indirect algorithms, Hoffmann and refineR. The established RIs differed significantly from those of low‐altitude regions, highlighting the need for region‐specific RIs to ensure accurate evaluation of coagulation disorders.
Banjiu Zhaxi, Danni Mu, Shengfang Ye, Chaochao Ma, Zhen Da, Yichen Ma, Yumeng Gao, Shensong Li, Yixicuomu, Zhaxiyangzong, Jinrong Pang, Mingjun Zhan, Ling Qiu, Qu Dan, Xinqi Cheng, Zhijuan Liu   +15 more
wiley   +1 more source

gene possibly associated with erythrocytosis

, 2019
In secondary erythrocytosis, the elevated red cell count is powered by factors outside the erythroid compartment, for instance by raised erythropoietin (EPO) synthesis based on congenital defects of the oxygen-sensing pathway.
Herr, Wolfgang, Wolfgang Herr, Grassinger, Jochen, Schelker, Roland Christian, Roland Christian Schelker, Jochen Grassinger   +5 more
core   +1 more source

Medical dilemmas – erythrocytosis

, 2020
Erythrocytosis is defined not only by an increase in the erythrocyte count, hemoglobin concentration, and hematocrit value, but also by the occurrence of specific symptoms, the intensity and frequency of which depend on the character of the initial ...
Lewandowski, Krzysztof; Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznań, Poland
core   +1 more source

A rare case of renal oncocytoma associated with erythrocytosis: case report

BMC Urology, 2006
Background Oncocytomas are benign tumors of the kidney that are usually diagnosed postoperatively due to differential diagnostic problems from renal cell carcinoma.
Tahmatzopoulos Anastasios, Tzakas Konstantinos, Radopoulos Demetrios   +2 more
doaj   +1 more source

Hemochromatosis Gene Mutation in Persons Developing Erythrocytosis on Combined Testosterone and SGLT-2 Inhibitor Therapy

Journal of Investigative Medicine High Impact Case Reports, 2022
In clinical trials, sodium-glucose cotransporter-2 inhibitors (SGLT-2i) use alone in persons with type 2 diabetes (T2D) or testosterone replacement therapy (TRT) prescription alone in men with hypogonadism was shown to lead to a modest but significant ...
Kamilya A. Schumacher BA, Aidar R. Gosmanov MD, PhD, FACE   +1 more
doaj   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

Veterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin, Ariadne Rein, Isabella de Almeida Fabris, Beatriz Gasser, Luiz Paulo Nogueira Aires, Bruna Bressianini Lima, Daniele Azevedo Gandra, Daniela Gomes da Silva, Ricardo Andrés Ramirez Uscategui, Gabriela Castro Lopes Evangelista, Marcus Antônio Rossi Feliciano, Paola Castro Moraes   +11 more
wiley   +1 more source