Results 51 to 60 of about 8,414 (207)

Blood p50 evaluation enhances diagnostic definition of isolated erythrocytosis.

, 2009
BACKGROUND: High oxygen-affinity haemoglobin variants and 2,3-diphosphoglycerate (2,3-DPG) deficiency are inherited diseases generating low tissue oxygen tension and erythropoietin-driven erythrocytosis, that characterizes the clinical phenotype of ...
Cazzola M, Pietra D, Elena C, Tedesco R, PASSAMONTI, FRANCESCO, Ammirabile M, Pagano L, Flagiello A, Arcaini L, Marcello AP, Rumi E, Vercellati C, Moratti R, Lazzarino M.   +13 more
core   +2 more sources

COEXISTENCE OF MULTIPLE GENE VARIANTS IN SOME PATIENTS WITH ERYTHROCYTOSES

Mediterranean Journal of Hematology and Infectious Diseases
Background: Erythrocytosis is a relatively common condition, however a large proportion of these patients (70%) remain without a clear etiologic explanation.
Andrea Benetti, Irene Bertozzi, PhD, MD, Giulio Ceolotto, Irene Cortella, Daniela Regazzo, Giacomo Biagetti, Elisabetta Cosi, Maria Luigia Randi, MD, Prof   +7 more
doaj   +1 more source

Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis

The Journal of Physiology, EarlyView.
Abstract figure legend Pharmacologically augmenting erythropoiesis with rEPO at sea level blunts the high altitude induced erythropoiesis. Abstract Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis.
Roy M. Salgado, Thomas A. Mayer, Gabrielle E. W. Giersch, Billie K. Alba, David E. Barney Jr, Aaron R. Caldwell, Nisha Charkoudian, Brandon M. Roberts, Afton D. Seeley, K. Riley Connor, Andrew M. Greenfield, Adam J. Luippold, Mark L. Plamper, Jermaine A. Ward, Shauna M. Ward, Benjamin J. Ryan   +15 more
wiley   +1 more source

The role of PHD2 mutations in the pathogenesis of erythrocytosis [PDF]

, 2014
The transcription of the erythropoietin (EPO) gene is tightly regulated by the hypoxia response pathway to maintain oxygen homeostasis. Elevations in serum EPO level may be reflected in an augmentation in the red cell mass, thereby causing erythrocytosis.
Arsenault, Patrick R, Lee, Frank S, McMullin, Mary Frances, Almeida, Helena, Schofield, Christopher J, Gardie, Betty, Chowdhury, Rasheduzzaman, Hoogewijs, David, Ewing, Joanne, Lambert, Frédéric, Percy, Melanie J, Bento, Celeste, Richard, Stéphane, Gardie B, Hoogewijs D, Lambert F, Chowdhury R, Percy MJ, Richard S, Ewing J, McMullin MF, Arsenault PR, Lee FS, Schofield CJ, Bento C, Almeida H   +25 more
core   +1 more source

PHARMACOLOGICAL TRIGGERS OF SECONDARY ERYTHROCYTOSIS

Клінічна та профілактична медицина
Introduction. Medicinal products are increasingly considered through the lens of their side effects, particularly as a possible factor in the development of secondary erythrocytosis.
Mariia A. Trypilka, Oksana M. Kostiukevych   +1 more
doaj   +1 more source

Elevational variation in heart mass and suppression of hypoxia‐induced right ventricle hypertrophy in Andean leaf‐eared mice (Phyllotis)

The Journal of Physiology, EarlyView.
Abstract figure legend In lowland mammals that ascend to high elevation, hypoxia‐induced changes in the pulmonary circulation can give rise to hypoxic pulmonary hypertension (HPH) and associated right‐ventricle (RV) hypertrophy. Andean mice with broad elevational ranges have greater heart mass relative to body size at higher elevations, but they ...
Naim M. Bautista, Nathanael D. Herrera, Marcial Quiroga‐Carmona, Chandrasekhar Natarajan, Adriana Rico‐Cernohorska, Jorge Salazar Bravo, Graham R. Scott, Guillermo D'Elía, Zachary A. Cheviron, Jay F. Storz   +9 more
wiley   +1 more source

Clinico-Hematological Patterns of Patients Presenting With Erythrocytosis

Pakistan Armed Forces Medical Journal
Objective: To assess the frequency of erythrocytosis and compare the clinical features and haematological parameters in patients presenting with primary and secondary erythrocytosis in the Pakistani population.
Shumaila Asghar, Asad Mahmood Abbasi, Jawad Zafar, Helen Mary Robert, Ayesha Khursheed, Sadia Ali   +5 more
doaj   +1 more source

Knockdown of mitotically associated long non‐coding RNA dysregulates endothelial functions, transcriptome and proteome

The Journal of Physiology, EarlyView.
Abstract figure legend Downregulation of mitotically associated long non‐coding RNA (MANCR) disturbs transcriptome and proteome in endothelial cells, possibly leading to endothelial and vascular dysfunction in preeclampsia. Abstract Preeclampsia (PE) is a hypertensive disorder during pregnancy, which is characterized by a wide spectrum of endothelial ...
Si‐Yan Zhang, Chi Zhou, Jing Zheng
wiley   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

European Journal of Haematology, Volume 117, Issue 6, Page 1421-1441, December 2026.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto, Silvia Sorella, Erminia Baldacci, Massimo Breccia, Sabina Chiaretti, Marcello Capriata, Livia Donzelli, Gianna Maria D'Elia, Salvatore Giacomo Morano, Ilaria Del Giudice, Maurizio Martelli, Cristina Santoro, Antonio Chistolini   +12 more
wiley   +1 more source

Hemochromatosis Gene Mutation in Persons Developing Erythrocytosis on Combined Testosterone and SGLT-2 Inhibitor Therapy

Journal of Investigative Medicine High Impact Case Reports, 2022
In clinical trials, sodium-glucose cotransporter-2 inhibitors (SGLT-2i) use alone in persons with type 2 diabetes (T2D) or testosterone replacement therapy (TRT) prescription alone in men with hypogonadism was shown to lead to a modest but significant ...
Kamilya A. Schumacher BA, Aidar R. Gosmanov MD, PhD, FACE   +1 more
doaj   +1 more source