Results 51 to 60 of about 7,152 (164)

Dapagliflozin does not impair microvascular hemorheology in type 2 diabetes mellitus: A multicenter randomized controlled trial (D‐PATH study)

open access: yesJournal of Diabetes Investigation, EarlyView.
Graphical abstract illustrating the study design, physiological rationale, and key findings of the D‐PATH trial. Dapagliflozin, an SGLT2 inhibitor, lowers HbA1c and body weight while increasing hematocrit and erythropoietin levels. Although an elevated hematocrit could theoretically increase blood viscosity and impair microcirculatory flow, ex vivo ...
Yuki Nakatani   +16 more
wiley   +1 more source

Juvenile erythrocytosis in children after liver transplantation: prevalence, risk factors and outcome [PDF]

open access: yes, 2020
Most reports of post-transplant erythrocytosis have involved kidney recipients and, so far, there have been no large studies of onset of erythrocytosis after orthotopic liver transplantation (OLT) in children.
Maria Caropreso   +8 more
core   +2 more sources

Clinico-Hematological Patterns of Patients Presenting With Erythrocytosis

open access: yesPakistan Armed Forces Medical Journal
Objective: To assess the frequency of erythrocytosis and compare the clinical features and haematological parameters in patients presenting with primary and secondary erythrocytosis in the Pakistani population.
Shumaila Asghar   +5 more
doaj   +1 more source

Nocturnal Sleep Breathing Patterns in Healthy Adolescents Residing at Very High Altitudes in Bolivia

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Data on sleep and respiratory patterns among adolescents residing at very high altitude (> 3500 m) remain scarce, and altitude‐related physiological differences may influence these parameters. Studying adolescents at different very high altitudes is crucial, as subtle environmental variations could affect sleep‐related oxygenation and ...
Keaton Patterson   +8 more
wiley   +1 more source

Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT A 7‐year‐old, male, castrated, mixed‐breed dog presented with right pelvic limb lameness and pain on posturing to defecate that began 1.5 years prior to presentation. Radiographs taken 8 months prior to presentation showed a small lytic lesion of the L6 vertebral body, and CBCs showed a persistently increased hematocrit (HCT) for at least 2 ...
Samuel V. Neal   +11 more
wiley   +1 more source

Erythrocytosis in a patient with chronic obstructive pulmonary disease [PDF]

open access: yes, 1998
Chronic obstructive pulmonary disease (COPD) can be accompanied by compensatory secondary erythrocytosis. However, the exact prevalence of secondary erythrocytosis in COPD is unknown.
Martani C   +5 more
core   +1 more source

Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations

open access: yesHaematologica, 2016
Erythrocytosis is a rare disorder characterized by increased red cell mass and elevated hemoglobin concentration and hematocrit. Several genetic variants have been identified as causes for erythrocytosis in genes belonging to different pathways including
Carme Camps   +9 more
doaj   +1 more source

Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Pharmacologically augmenting erythropoiesis with rEPO at sea level blunts the high altitude induced erythropoiesis. Abstract Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis.
Roy M. Salgado   +15 more
wiley   +1 more source

The role of PHD2 mutations in the pathogenesis of erythrocytosis [PDF]

open access: yes, 2014
The transcription of the erythropoietin (EPO) gene is tightly regulated by the hypoxia response pathway to maintain oxygen homeostasis. Elevations in serum EPO level may be reflected in an augmentation in the red cell mass, thereby causing erythrocytosis.
Arsenault, Patrick R   +12 more
core   +1 more source

Elevational variation in heart mass and suppression of hypoxia‐induced right ventricle hypertrophy in Andean leaf‐eared mice (Phyllotis)

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In lowland mammals that ascend to high elevation, hypoxia‐induced changes in the pulmonary circulation can give rise to hypoxic pulmonary hypertension (HPH) and associated right‐ventricle (RV) hypertrophy. Andean mice with broad elevational ranges have greater heart mass relative to body size at higher elevations, but they ...
Naim M. Bautista   +9 more
wiley   +1 more source

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