Results 51 to 60 of about 11,080 (216)

Mouse models of myeloproliferative Neoplasms: JAK of all grades. (Review) [PDF]

, 2011
In 2005, several groups identified a single gain-of-function point mutation in the JAK2 kinase that was present in the majority of patients with myeloproliferative neoplasms (MPNs).
Li, J., Kent, D.G., Chen, E., Green, A.R., Li, J., Kent, D.G., Chen, E., Green, A.R.   +7 more
core   +2 more sources

RECENT INSIGHTS INTO SECONDARY ERYTHROCYTOSIS: PART I. ETIOLOGY

Клінічна та профілактична медицина
Introduction. The development of secondary erythrocytosis is associated with a wide range of both hereditary and acquired pathological conditions. Modern advances in medicine have deepened the understanding of the etiology and pathogenesis of secondary ...
Mariia A. Trypilka, Oksana M. Kostiukevych, Lesia K. Benkovska   +2 more
doaj   +1 more source

Enalaprilat and losartan decrease erythroid precursors frequency in cells from patients with polycythemia vera

Hematology, 2023
Objective: Polycythemia Vera (PV) is a myeloproliferative neoplasm characterized by the overproduction of red blood cells. First-line therapies are directed at lowering hematocrit levels. After the discovery of a mutation in the Janus kinase 2 (JAK2V617F)
Angela Bozza, Martina Bernardi, Daniela Catanzaro, Katia Chieregato, Anna Merlo, Giuseppe Astori   +5 more
doaj   +1 more source

Erythrocytosis due to PHD2 Mutations: A Review of Clinical Presentation, Diagnosis, and Genetics

Case Reports in Hematology, 2016
The association of mutations in the PHD2 protein of the hypoxia-sensing pathway and erythrocytosis has only been established in the last decade. Here we report the case of a novel PHD2 gene mutation in a patient with erythrocytosis and summarize all ...
Rachel Wilson, Nausheen Syed, Prabodh Shah   +2 more
doaj   +1 more source

Myeloproliferative neoplasms: a review of diagnostic criteria and clinical aspects [PDF]

, 2010
Chronic myeloproliferative disorders, currently called myeloproliferative neoplasms (MPN), according to the 4th edition of the World Health Organization (WHO) classification are clonal diseases of hematopoietic stem cells, in which there is increased ...
Chauffaille, Maria de Lourdes Lopes Ferrari
core   +1 more source

Prognostic Value of Perioperative Anemia in Neurosurgical‐Oncological Treatment of Spinal Metastases

International Journal of Cancer, EarlyView.
High perioperative morbidity in patients undergoing surgery for spinal metastases highlights the need to identify modifiable risk factors, particularly the underexplored role of anemia. This study assessed associations between perioperative hemoglobin levels and complications, recurrence, and mortality in patients treated surgically for spinal ...
Marija Janjic, Logman Khalafov, Juliane Dittmer, Saif‐Eldin Abedellatif, Tim Lampmann, Harun Asoglu, Mohammed Jaber, Haitham Alenezi, Muriel Heimann, Matthias Schneider, Motaz Hamed, Marcus Thudium, Hartmut Vatter, Mohammed Banat   +13 more
wiley   +1 more source

Arterial oxygen content is precisely maintained by graded erythrocytotic responses in settings of high/normal serum iron levels, and predicts exercise capacity: an observational study of hypoxaemic patients with pulmonary arteriovenous malformations.

, 2014
Oxygen, haemoglobin and cardiac output are integrated components of oxygen transport: each gram of haemoglobin transports 1.34 mls of oxygen in the blood.
AD Kjeldsen, AM Evans, AN Friedman, BE Phillips, BM Silva, BR O'Driscoll, CG Mason, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, Claire L. Shovlin, CM Fletcher, D Pennington, DZ Levett, E McLean, ER Chilvers, H Finnamore, Hannah C. Tighe, IS Anand, JA Dutton, JA Livesey, James E. Jackson, JE Van de Pette, JJ Mager, JL Hart, L Boyer, LC Ou, Louisa C. Williams, LS Valberg, M Hu, M Moussouttas, ME Faughnan, MF McMullin, MK Whyte, MK Whyte, MP Grocott, MW van Gent, P Gupta, P Shovlin CL Wilmshurst, PB Terry, PC Hébert, PM Sondel, RC Hewes, RD Thompson, S Honda, T Ueki, Tracey Rouault, V Cottin, Vatshalan Santhirapala, WB Porter, WS Smellie   +53 more
core   +2 more sources

Effect of angiotensin-converting enzyme gene insertion/deletion polymorphism and angiotensin-converting enzyme inhibition on erythropoiesis in patients on haemodialysis. [PDF]

, 2018
BACKGROUND: Angiotensin-converting enzyme inhibitors (ACEis) improve survival; however, their effect on erythropoiesis remains a matter of debate in this population.
Ambrus, Csaba, Kiss, István, Kiss, Zoltán, Kulcsar I, on behalf of the ACEGENE-BB_HU workgroup, Szegedi J   +5 more
core   +1 more source

ERYTHROCYTOSIS IN CHILDREN: CASE REPORT

Slovenska pediatrija
Erythrocytosis is a condition characterized by an increased mass of red blood cells, which manifests as an elevated concentration of hemoglobin, increased count of red blood cells, and increased hematocrit levels.
Teja Leban, Janez Jazbec
doaj   +1 more source

A rare case of renal oncocytoma associated with erythrocytosis: case report

BMC Urology, 2006
Background Oncocytomas are benign tumors of the kidney that are usually diagnosed postoperatively due to differential diagnostic problems from renal cell carcinoma.
Tahmatzopoulos Anastasios, Tzakas Konstantinos, Radopoulos Demetrios   +2 more
doaj   +1 more source