Results 161 to 170 of about 156,163 (270)

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, Volume 14, Issue 4, Page 978-991, May 2026.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

A streamlined, nanopore-compatible 5PSeq protocol for rapid phenotypic antimicrobial sensitivity testing. [PDF]

Cell Rep Methods
Liu H, Huch S, Hull R, Garcia FR, Nersisyan L, Yin X, Chen WH, Du J, Pelechano V.   +8 more
europepmc   +1 more source

First Description and Characterisation of Lactococcus garvieae Strains Causing Septicaemic Disease in Farmed Sea Bass (Dicentrarchus labrax; Linnaeus) in Spain

Journal of Fish Diseases, Volume 49, Issue 5, May 2026.
ABSTRACT This study presents the first description and characterisation of Lactococcus garvieae isolated from diseased European sea bass (Dicentrarchus labrax) farmed in Spain. During autumn 2023, two fish farms were affected by infectious outbreaks causing moderate cumulative fish mortality (5%–10%). Diseased fish showed clinical signs of haemorrhagic
Belén Fouz, Evelyn Carballeda‐Carrasco, Javier Barriga‐Cuartero, Yolanda Torres‐Corral, Álvaro Robles, Carlos Zarza, Ysabel Santos   +6 more
wiley   +1 more source

A novel TetR-type repressor directly modulates precursor supply and utilization for erythromycin biosynthesis. [PDF]

Synth Syst Biotechnol
Wu P, Meng Z, Shu Y, Chen K, Xu Z, Huang X, Zhang B, Liu J, Wu H.   +8 more
europepmc   +1 more source

One Health Genomic Analysis of Methicillin‐Resistant Staphylococcus spp. From Humans, Cats, and Dogs in a Veterinary Hospital in Central Chile

Zoonoses and Public Health, Volume 73, Issue 3, Page 205-217, May 2026.
ABSTRACT Introduction The emergence of methicillin‐resistant Staphylococcus species (MRS) poses a growing threat to both human and veterinary health. Methods We performed a comparative genomic characterisation of 49 methicillin‐resistant Staphylococcus isolates collected from humans, dogs, and cats in a veterinary hospital from Central Chile.
Daniel Garrido, Danny Fuentes‐Castillo, Leslye Camila del Río, Jorge Barraza‐Schulmeyer, Felipe Melis, Patricia García, Carla Flores‐Yáñez, Pamela Thomson   +7 more
wiley   +1 more source

<i>In vitro</i> activity of MRS-2541, a novel MetRS inhibitor, against a selection of resistant gram-positive organisms associated with serious hospital infections. [PDF]

Microbiol Spectr
Domagala J, Jahanbakhsh S, Mendez AK, Pillar CM, Marra A, Hufnagel DA, Molasky NMR, Zhang Z, Fan E, Reyna D, Lipka E, Buckner FS.   +11 more
europepmc   +1 more source

Allium‐Derived Compounds Against Multidrug‐Resistant Bacteria: Antibacterial Activity and Synergistic Effects

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
This study evaluates four compounds derived from the genus Allium against 330 multidrug‐resistant bacteria. Propyl‐propane‐thiosulfonate (PTSO) exhibits the highest activity, particularly against Gram‐positive strains, while Gram‐negative bacteria are less affected.
Antonio Sorlózano‐Puerto, Yariel Figueroa‐Vega, Pablo Martín‐Valenzuela, José Manuel de la Torre‐Ramírez, Alberto Baños, José Gutiérrez‐Fernández   +5 more
wiley   +1 more source

Antibiotic Prophylaxis and Treatment of Neonatal Group B Streptococcus Disease in the Era of Antimicrobial Resistance. [PDF]

Antibiotics (Basel)
Tzialla C, Salomè S, Mondì V, Salvo V, Berardi A.   +4 more
europepmc   +1 more source

Development of Styryl‐Modified 3,4‐Dihydropyrimidin‐2(1H)‐ones as Potential Antitumor Agents

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Styryl‐modified 3,4‐dihydropyrimidin‐2(1H)‐ones (DHPMs), designed from the Eg5 inhibitor monastrol, show markedly enhanced antiproliferative activity in HeLa and MCF‐7 cancer cells. Lead compounds 16 and 17 trigger apoptosis through cell‐line‐specific pathways and downregulate c‐Myc, emerging as promising anticancer candidates.
Konstantinos Panagoulias, Woonghee Kim, Murat Ozdemir, Busra Turan, Adil Mardinoglu, Hasan Turkez, Daniela Trisciuzzi, Orazio Nicolotti, Antonio Di Stefano, Stamatia Vassiliou, Ivana Cacciatore   +10 more
wiley   +1 more source

Antibiotic Resistance of Campylobacter Species Isolated From Foods, Animals and Humans in Iran Through One Health Approach: A Systematic Review and Meta-Analysis. [PDF]

Vet Med Sci
Salmani F, Mohamadi S, Tasara T, Ansarifar E, Sadighara P, Zeinali T.   +5 more
europepmc   +1 more source