Results 181 to 190 of about 110,927 (303)

Enterococcus faecalis Extracellular Vesicles Deliver the Bacterial GTPase Obg to Hijack mTOR Signalling in Hepatocellular Carcinoma

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
E. faecalis is enriched in HCC tissue and can promote liver tumourigenesis by activating mTOR signalling pathway. Obg derived from E. faecalis extracellular vesicles (EVs) is a GTPase physically interacts with mTOR, and acts as an interkingdom activator of mTOR. EF‐Obg expression level in HCC tissue correlates with poor prognosis in HCC patients.
Ning Ma   +18 more
wiley   +1 more source

DKK1 Targeting in Corneal Schwann Cells Rescues Axonal Regeneration and Mechanosensory Function After Corneal Injury

open access: yesJournal of Neuroscience Research, Volume 104, Issue 6, June 2026.
The schematic illustrates that corneal injury imparted by a stromal incision or by toxic chemical exposure causes corneal Schwann cells (cSCs) and axons to degenerate rapidly, resulting in impaired mechanosensory function. We hypothesized that repair cSCs, which develop post injury, are an as‐yet‐untested cellular target for axonal regeneration.
Michael Li   +6 more
wiley   +1 more source

Corynebacterium ulcerans Diphtheria in Japan

open access: yesEmerging Infectious Diseases, 2003
Akio Hatanaka   +7 more
doaj   +1 more source

Detecting <i>erm</i>-Mediated Inducible Macrolide-Lincosamide-Streptogramin B Resistance in Anaerobic Clinical Isolates. [PDF]

open access: yesAntibiotics (Basel)
Thalmann FD   +6 more
europepmc   +1 more source

Characteristics and Clinical Outcomes of Patients With Hidradenitis Suppurativa (HS) Treated With Bimekizumab: A Canadian Retrospective Chart Review

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 627-631, June 2026.
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease characterised by painful nodules, abscesses, and draining and non‐draining tunnels. Currently, there are two biologics approved in Canada for the treatment of moderate‐to‐severe HS, adalimumab (anti‐TNF) and secukinumab (anti‐IL‐17A).
Irina Turchin   +4 more
wiley   +1 more source

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 385-393, June 2026.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson   +4 more
wiley   +1 more source

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