Results 71 to 80 of about 99,664 (224)

The Immunomodulatory Effects of Macrolides—A Systematic Review of the Underlying Mechanisms

Frontiers in Immunology, 2018
BackgroundThe mechanisms underlying the non-antimicrobial immunomodulatory properties of macrolides are not well understood.ObjectivesTo systematically review the evidence for the immunomodulatory properties of macrolides in humans and to describe the ...
Petra Zimmermann, Petra Zimmermann, Petra Zimmermann, Petra Zimmermann, Victoria C. Ziesenitz, Nigel Curtis, Nigel Curtis, Nigel Curtis, Nicole Ritz, Nicole Ritz, Nicole Ritz   +10 more
doaj   +1 more source

Heatwave‐Resilient Cuticular Microbiota Protect the Leaf Beetle Plagiodera versicolora From Fungal Infection

Integrative Zoology, EarlyView.
ABSTRACT The increasing frequency and intensity of heatwaves—extreme thermal events characterized by prolonged supra‐optimal temperatures—exert profound impacts on global ecosystem stability and species interactions. While the disruptive effects of thermal stress on host physiology and gut microbiota are well documented, the role of cuticular ...
Jiyu Wu, Chengjie Tu, Rongshan Fan, Letian Xu   +3 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Clinical And Bacteriological Impact Of Clarithromycin In Streptococcal Pharyngitis: Findings From A Meta-Analysis Of Clinical Trials

Drug Design, Development and Therapy, 2019
Daryl J Hoban,1 Jos Nauta2 1Department of Medical Microbiology and Infectious Disease, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada; 2Department of Innovation & Development, Established Pharmaceuticals Division ...
Hoban DJ, Nauta J
doaj  

Antimicrobial resistance patterns in bacterial isolates from mice and rats in Australian laboratory rodent facilities between 2015 and 2024

Australian Veterinary Journal, EarlyView.
Antimicrobial resistance (AMR) is a critical global challenge threatening human and animal health, food security and economic stability. Despite advances in understanding AMR trends of bacteria from humans, domestic animals, wildlife and environmental sources, there is limited understanding regarding AMR profiles of bacteria isolated from laboratory ...
RS Wilcox, L Rasmussen, CC Hill, LYP Fung, EN Simmonds, JM Devlin, MS Marenda, CR Wilks   +7 more
wiley   +1 more source

Clinical outcomes of empirical topical nifuratel or nitrofurantoin in Streptococcus pyogenes vulvovaginitis: A retrospective study

International Journal of Gynecology &Obstetrics, EarlyView.
Marek Stefan, Kristyna Krogh, Jaroslava Zikova, Marta Novackova, Marcela Krutova   +4 more
wiley   +1 more source

Triggering SORL1 Expression Restricts ccRCC Progression by Inducing Ubiquitination‐Mediated c‐Myc Degradation

Cancer Science, EarlyView.
Targeted triggering of SORL1 expression through a novel MPOC delivery system could inhibit ccRCC progression through binding to TRIM22 and further promoting ubiquitination‐mediated C‐MYC degradation, thereby facilitating the inhibition of oxidative phosphorylation through transcriptional repression of ACO2 and IDH2.
Keyi Wang, Wei Song, Qi Bai, Shaoze Shen, Xiao Lu, Chenxuan Su, Shi Yang, Yidi Wang, Yu Xia, Rui Zan, Shuai Jiang, Jianming Guo   +11 more
wiley   +1 more source

Enigma of Folliculitis Decalvans in Two Pediatric Sisters, Treated with Low-Dose Isotretinoin and Erythromycin

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Folliculitis decalvans (FD) is a rare form of primary cicatricial alopecia, characterized by chronic inflammation and destruction of hair follicles, occurring predominantly in young to middle-aged men and uncommon in women under 30 years of age ...
Amogh Ratnaparkhi, Praneet Awake, Anand Bhosale, Prabodh Gaikwad, Neeta Gokhale, Aditi Shende, Vivek Dugad, Rajan Bindu, Prateek Awake, Shruti Dewang   +9 more
doaj   +1 more source

Evolution of Bacterial Yield and Antimicrobial Resistance in Chronic Rhinosinusitis Patients in a Dedicated Sinus Centre

Clinical Otolaryngology, EarlyView.
ABSTRACT Background Antibiotics are frequently prescribed for acute exacerbations of chronic rhinosinusitis (CRS). However, antimicrobial resistance presents a challenge for the ongoing and future management of CRS patients. Objective This study aims to examine the current and past microbiological yield and antimicrobial resistance profile in a ...
Timoleon Siempis, Zhu Yeap, Shifa Ali, Carl M. Philpott   +3 more
wiley   +1 more source

Reprogramming of gastric motility with "pulse therapy" (metoclopramide and erythromycin) in severe gastroparesis

Journal of Family Medicine and Primary Care, 2013
Gastroparesis is a very common condition, however many times it becomes difficult to manage even after long-term treatment due to multiple etiologies or improper therapy. Patients with severe gastroparesis are considered candidates for gastric electrical
Shamik Shah, Dharmesh Kaswala, Nishith Patel, Sunita Sood, Zamir Brelvi   +4 more
doaj   +1 more source