Results 171 to 180 of about 85,932 (276)

Whole Blood Transcriptomic Analysis of Sickle Cell Trait. [PDF]

Eur J Haematol
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Johnson M, Cai Y, Vasconcelos AG, Orchard P, Auer PL, Lettre G, Wen J, Franceschini N, Kooperberg C, Sun W, Hsu L, Raffield LM, Reiner AP.   +12 more
europepmc   +2 more sources

In response to stress: quicker, yet bigger. [PDF]

Blood Adv
Palis J.
europepmc   +1 more source

Management of neonatal massive hemorrhage: A narrative review

Transfusion, EarlyView.
Cheryl S. L. Chooi, Mary Claire Simmonds, Laura Fisher, Tara Crawford, Michael J. Stark, Scott Morris, Marcus Brecht, Fiona Taverner   +7 more
wiley   +1 more source

Altitude or heat training to increase haemoglobin mass and endurance exercise performance in elite sport

The Journal of Physiology, EarlyView.
Abstract figure legend Upper panel, high‐altitude training typically encompasses 3–4 weeks of altitude exposure combined with training either at altitude or at sea level. Following this, a response for haemoglobin mass (Hbmass) is seen in two of three studies, which coincides with some performance gains in <50% of studies.
Carsten Lundby, Paul Robach
wiley   +1 more source

Osteocyte-derived erythroferrone regulates liver hepcidin during stress erythropoiesis. [PDF]

Blood Adv
Myneni VD, Parashar A, Vitale-Cross L, Szalayova I, de Castro LF, Mezey E.   +5 more
europepmc   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Post-translational Modifications in Proteins: Prediction Methods, Biological Functions, and Diseases. [PDF]

MedComm (2020)
Zhang S, Li J, Chen M, Huang H.
europepmc   +1 more source

Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints

The Journal of Physiology, EarlyView.
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero, Franck Brocherie, Olivier Girard, Nathan Townsend, Chris J. McNeil, Grégoire P. Millet   +5 more
wiley   +1 more source

Synergistic effects of luspatercept and cyclosporine A in lower-risk myelodysplastic syndrome with red cell aplasia: Two case insights. [PDF]

Leuk Res Rep
Jo T, Sakai T, Noguchi K, Yamaguchi K, Umemoto K, Abe K, Shigematsu K.   +6 more
europepmc   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source