Abstract High‐altitude exposure increases haemoglobin mass (Hbmass), a key determinant of arterial oxygen‐carrying capacity, but following descent this adaptation can regress toward baseline within 7 days. Long‐term heat acclimation has emerged as an alternative stimulus for Hbmass expansion; however, whether post‐altitude passive‐heat exposure can ...
Elliott J. Jenkins +12 more
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Brazilin From Biancaea sappan as a Multi-Target Candidate in Thalassaemia: Mechanistic Insights Into Iron Chelation, Antioxidant Activity, and Potential JAK2 Modulation. [PDF]
Youngest R +3 more
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Abstract figure legend Upper panel, high‐altitude training typically encompasses 3–4 weeks of altitude exposure combined with training either at altitude or at sea level. Following this, a response for haemoglobin mass (Hbmass) is seen in two of three studies, which coincides with some performance gains in <50% of studies.
Carsten Lundby, Paul Robach
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The Role of Micronutrient Deficiencies in Nutritional Anemia Beyond Iron: An Expert Perspective on the Scope and Strength of the Current Evidence. [PDF]
Farrell CC +11 more
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Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson +1 more
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Impaired iron balance and erythrocytosis: a complex relationship. [PDF]
Gendrot B +4 more
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What Is Your Diagnosis? Abnormal WNR Scattergram From the Sysmex XN‐1000V in a Dog
Veterinary Clinical Pathology, EarlyView.
Javier Martínez‐Caro +3 more
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Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero +5 more
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The role and therapeutic potential of nanotechnology-mediated ferroptosis regulation in myelodysplastic syndromes. [PDF]
An W +8 more
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Mechanisms of haemoglobin mass expansion following heat stress
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins +4 more
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