Results 201 to 210 of about 94,345 (348)

Comparative effectiveness of hypoxia-inducible factor prolyl hydroxylase inhibitors versus erythropoiesis-stimulating agents on prognosis in non-dialysis chronic kidney disease: a propensity-matched cohort study

Hou, Yi-Chou, Wu, Chia-Lin, Tseng, Wei-Cheng, Wang, Joshua, Lu, Kuo-Cheng, Zheng, Cai-Mei, Liu, Jia-Sin, Kuo, Ko-Lin, Tarng, Der-Cherng   +8 more
openalex   +1 more source

Model‐Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 322-335, February 2026.
Model‐informed drug development (MIDD) played a crucial role in the successful development and regulatory approval of daprodustat, a novel oral hypoxia‐inducible factor prolyl hydroxylase (HIF‐PHI) inhibitor aimed at treating anemia in chronic kidney disease patients.
Kelly M. Mahar, Shuying Yang, Brendan Johnson, Sandra A.G. Visser, Paul van den Berg, Martijn van Noort, Teun M. Post   +6 more
wiley   +1 more source

Hemoglobin and human longevity: integrating oxygen transport, redox biology, and aging pathways - a narrative review. [PDF]

Ann Med Surg (Lond)
Obeagu EI.
europepmc   +1 more source

Erythropoiesis in preleukemia [PDF]

, 1978
HP Koeffler, MJ Cline, DW Golde
openalex   +1 more source

Acute Hypoxia Decreases Maximum Fat Oxidation Rate During Step Incremental Exercise Normalized to Respiratory Compensation Point

European Journal of Sport Science, Volume 26, Issue 2, February 2026.
ABSTRACT Whether fat oxidation (FATox) is altered during exercise in hypoxia remains equivocal due to differences in experimental protocols. Furthermore, to date no investigation has reported the effect of hypoxia on maximal fat oxidation rate (MFO).
Youmna Elsayed Hassanein, Dania Ibrahim, Juan M. Murias, Nathan Townsend   +3 more
wiley   +1 more source

Retraction: Investigating the relationship between erythropoiesis-stimulating agents and mortality in hemodialysis patients: A systematic review and meta-analysis. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Transferability of Real World Evidence to Support HTA Recommendations in Lower Income European Countries

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Lower income European countries (LIECs) have more limited financial resources to cover high‐cost technologies in rare diseases than higher income European countries (HIECs). Our study explores how treatment recommendations in myelodysplastic syndrome (MDS) can be supported in LIECS by transferring real‐world evidence (RWE ...
Zoltán Kaló, Guenka Petrova, Bertalan Németh, Petra Došenović Bonča, Diana Delnoij, Alastair Bennett, Konstantin Tachkov, Yingying Zhang, Noemi Kreif, Saskia Knies, Iga Lipska, Tomas Tesar, Zornitsa Mitkova, Johan Ponten, Anders Viberg, Marian‐Sorin Paveliu, Oresta Piniazkho, Adina Turcu‐Stiolica, Tomáš Doležal, Michal Staňák, Alima Almadiyeva, Rok Hren, Dinko Vitezić, Zsuzsanna Petykó, Wim Goettsch, Andrea Manca   +25 more
wiley   +1 more source

Prpf4 sequentially regulates the expansion and maturation of erythrocyte through distinct mechanisms. [PDF]

Cell Death Discov
Deng Z, Huang S, Pei Y, Li H, Dong Y, Li Y, Ran Q, Liu X, Feng Y, Wang Q, Guo Z, Huang S.   +11 more
europepmc   +1 more source

Hydrolyzed Milk-Derived Peptides Promote Erythropoietin Pathways and Hematologic Recovery: A Cross-Species Analysis. [PDF]

Molecules
Zang L, Yokota A, Nakai M, Fukada K, Nishimura N, Shimada Y.   +5 more
europepmc   +1 more source

Fetal erythropoiesis and hemoglobin regulation in the context of maternal obesity

Zhongyun Kou, Md Nazmul Hossain, Li Wei Chen, S Islam, Xinrui Li, Chaeyoung Shin, Qiaorong Cui, Jeanene M. de Avila, Mei-Jun Zhu, ‬Min Du   +9 more
openalex   +1 more source