Results 121 to 130 of about 601 (148)

PORT-77, a Novel and Potent Inhibitor of ABCG2, Protects Against Skin Photo Toxicity and Liver Damage in a Mouse Model of Erythropoietic Protoporphyria (EPP)

Blood
Introduction PORT-77 is an orally bioavailable inhibitor of the ABCG2 (also known as BCRP) transport protein and is under development for the treatment of EPP. EPP is a rare, genetic form of photodermatosis resulting from autosomal recessive mutations in ferrochelatase (FECH ...
Bhavik Shah, Edmond Huang, Yvonne Pak, Chris Henry, Sunita Babbar, Athiwat Hutchaleelaha, Robert Zamboni, Xiaochao Ma, Pete Schmidt, Morgan Paull, Uma Sinha   +10 more
openaire   +1 more source

[Atypically localized persistent skin changes in erythropoietic protoporphyria (EPP)--histologic and electron microscopic findings (author's transl)].

Zeitschrift fur Hautkrankheiten, 1981
The case of a 29 year old man is presented, who showed 'sunburn like' reactions following short exposures to light since early childhood. Demonstration of fluorocytes and analysis of porphyrins confirmed the diagnosis of erythropoietic protoporphyria (EPP).
W, Meigel, G, Schaeg, G, Goerz
openaire   +1 more source

Afamelanotide for prevention of phototoxicity in erythropoietic protoporphyria

Expert Review of Clinical Pharmacology, 2021
Janneke Langendonk, Debby Wensink, Margreet Wagenmakers   +2 more
exaly  

Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria

Genetics in Medicine, 2021
Zhaozhong Zhu, Xihong Lin, Corbin Quick   +2 more
exaly  

Bitopertin, a Selective Glycine Transporter 1 Inhibitor, Reduced Protoporphyrin IX (PPIX) Level and Improved Liver Fibrosis in a Mouse Model of Erythropoietic Protoporphyria (EPP)

Blood, 2022
Min Wu, Sarah Ducamp, Yi Xiang, Juan Putra, Mark D. Fleming, Brian MacDonald, Paul J Schmidt   +6 more
openaire   +1 more source

Prospective observational pilot study of quantitative light dosimetry in erythropoietic protoporphyria

Journal of the American Academy of Dermatology, 2023
Sarina B Elmariah
exaly  

Genetic Analysis of Erythropoietic Protoporphyria (EPP) the Erythrocyte Fluorescence Method

1968
K. D. Wuepper, J. H. Epstein
openaire   +1 more source

Remission of erythropoietic protoporphyria (EPP) during pregnancy – Experience of two patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft
Gressenberger Paul, Hofer Angelika
openaire   +2 more sources

Erythropoietic Protoporphyria (EPP)

2019
openaire   +1 more source

Oocyte Cryopreservation and Delayed Pre-Implantation Genetic Diagnosis in the Setting of Erythropoietic Protoporphyria (EPP): A Case Report

Fertility and Sterility, 2014
Bruce D. Pier, Janet F. McLaren, G. Wright Bates   +2 more
openaire   +1 more source