Results 111 to 120 of about 187,553 (368)
Cloning and expression of codon-optimized recombinant darbepoetin alfa in Leishmania tarentolae T7-TR [PDF]
, 2016 Darbepoetin alfa is an engineered and hyperglycosylated analog of recombinant human erythropoietin (EPO) which is used as a drug in treating anemia in patients with chronic kidney failure and cancer.
Fard-Esfahani, P. +8 more
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The Discovery of Erythropoietin
ASAIO Journal, 1993 A personal vignette of life as a resident and fellow at the Yale New Haven Hospital in the early 1950s follows. John Peters and his associates created a superb renal center at Yale New Haven, and they instilled in me a respect for quantitative measurements and a love for simple physiologic concepts. The environment was ideal for clinical and laboratory
openaire +4 more sources
Neuroprotective effects of erythropoietin on rat retinas subjected to oligemia
Clinics, 2018 OBJECTIVES: Erythropoietin may have neuroprotective potential after ischemia of the central nervous system. Here, we conducted a study to characterize the protective effects of erythropoietin on retinal ganglion cells and gliotic reactions in an ...
Litia Alves de Carvalho +7 more
doaj +1 more source
Current Problems in Pediatrics, 1999 Current Problems in Pediatrics 29 (1999) 133-149.
Division of Neonatolgy, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610-0296, USA ( host institution ) +1 more
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Research progress of neurovascular units involved in ischemic stroke
Ibrain, EarlyView.The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang +4 more
wiley +1 more source
Neuroprotective effect of erythropoietin on anesthesia-induced neurotoxicity through the modulation of autophagy in [PDF]
Korean Journal of AnesthesiologyBackground The anti-oxidative, anti-inflammatory, and anti-apoptotic effects of erythropoietin may provide neuroprotective effects. Erythropoietin also modulates autophagy signaling that may play a role in anesthesia-induced neurotoxicity (AIN).
Bon-Wook Koo +5 more
doaj +1 more source
Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia [PDF]
, 2010 Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Alessandra Spiga +7 more
core +1 more source
Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats
Journal of Applied Toxicology, EarlyView.ABSTRACT Smoking is a major public health concern worldwide. The toxic components of cigarettes, such as nicotine, can cause abuse, dependence, and tissue damage. This study aimed to evaluate the effects of exposure to cigarette smoke on the renal morphology of Wistar rats.
Cristiane Gomes Fernandes Freire +9 more
wiley +1 more source
Биопрепараты: Профилактика, диагностика, лечение, 2018 The method for the assessment of biological activity of erythropoietin preparations in vitro on TF-1 sensitive cells culture has been developed. The special characteristics of measurements and calculations of the biological activity of erythropoietin ...
N. A. Gavrilova +3 more
doaj
Erythropoietin and Erythropoiesis in Anemic Man Following Androgens [PDF]
, 1969 Raymond Alexanian
openalex +1 more source