Results 121 to 130 of about 82,538 (246)
Abstract Background The high‐prevalence Emm antigen is an epitope on the GPI (glycosylphosphatidylinositol) glycolipid backbone, which anchors proteins to the cell surface. Inherited loss‐of‐function of PIGG (or PIGO) results in the rare Emm− red cell (RBC) phenotype and is associated with congenital disorders of glycosylation (CDG).
Alastair Murray +8 more
wiley +1 more source
The stages in standardizing erythropoietin preparations
Preparations of recombinant human erythropoietin (rhEPO) are included in the list of vital and essential drugs for medical use. When evaluating the quality of EPO preparations during the manufacturing process, under the state marketing authorization and ...
A. K. Yakovlev +7 more
doaj
A new biochemical effect of erythropoietin
Erythropoietin stimulated lactoperoxidase (LP) or horseradishperoxidase (HRP) catalyzed iodination of tyrosine, the stimulation being more pronounced in case of LP.
Ray, Pradip K. +2 more
core +1 more source
Erythropoietin Production in the Kidney
The hormone erythropoietin stimulates erythrocyte production and therefore regulates the oxygen capacity of the blood. Hypoxia promotes erythropoietin formation by stimulating the transcription of the erythropoietin gene in the kidney and, to a lesser ...
A Kurtz, C Bauer
core +1 more source
Abstract High‐altitude exposure increases haemoglobin mass (Hbmass), a key determinant of arterial oxygen‐carrying capacity, but following descent this adaptation can regress toward baseline within 7 days. Long‐term heat acclimation has emerged as an alternative stimulus for Hbmass expansion; however, whether post‐altitude passive‐heat exposure can ...
Elliott J. Jenkins +12 more
wiley +1 more source
Erythropoietin: current aspects and prospects
Authors have reviewed recent literature on erythropoietin. They report new information regarding synthesis, modulation, changes during several diseases and the possibility for a clinical use of erythropoietin for the correction of many anaemias.
CERUSO D. +5 more
core
Exercise intolerance and impaired aerobic capacity in heart transplant recipients
Abstract Heart transplant recipients exhibit reduced exercise tolerance and persistently diminished aerobic capacity despite exercise training. Exercise tolerance depends on integrated oxygen transport and utilization, which are impaired in heart transplant recipients.
Fred W. Kolkhorst +2 more
wiley +1 more source
Abstract Chronic shiftwork can impair autonomic cardiovascular regulation and immune homeostasis. However, the interaction between occupational status and physical activity level in military police officers remains incompletely understood. This cross‐sectional factorial study included 102 men stratified according to occupational status and physical ...
Hélida C. Aquino‐Santos +11 more
wiley +1 more source
Exogenous ketosis in breath‐hold diving: Promise, paradox and physiological risk
Abstract Exogenous ketosis induced by ketone ester (KE) ingestion has attracted growing interest as a potential strategy to enhance physiological tolerance to reduced O2 availability. Reported benefits arise largely from KE‐induced hyperventilation, which can improve systemic and tissue oxygenation during altitude exposure and hypoxic exercise ...
Ivan Drviš +5 more
wiley +1 more source
The ‘lactate paradox’ revisited after 35 years: In memoriam Paolo Cerretelli
Abstract Some decades ago significant scientific interest was raised by the concept of the ‘lactate paradox’ occurring during altitude acclimatization. In short, in acute hypoxia blood lactate− concentration ([La]b) is higher, compared to normoxia, at any given submaximal work rate, whereas peak [La]b at exhausting exercise is unchanged.
Bruno Grassi
wiley +1 more source

