Results 121 to 130 of about 82,538 (246)

A PIGG congenital disorder of glycosylation (PIGG‐CDG) variant associated with an Emm− red blood cell phenotype in a pediatric patient

open access: yesTransfusion, EarlyView.
Abstract Background The high‐prevalence Emm antigen is an epitope on the GPI (glycosylphosphatidylinositol) glycolipid backbone, which anchors proteins to the cell surface. Inherited loss‐of‐function of PIGG (or PIGO) results in the rare Emm− red cell (RBC) phenotype and is associated with congenital disorders of glycosylation (CDG).
Alastair Murray   +8 more
wiley   +1 more source

The stages in standardizing erythropoietin preparations

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
Preparations of recombinant human erythropoietin (rhEPO) are included in the list of vital and essential drugs for medical use. When evaluating the quality of EPO preparations during the manufacturing process, under the state marketing authorization and ...
A. K. Yakovlev   +7 more
doaj  

A new biochemical effect of erythropoietin

open access: yes, 1973
Erythropoietin stimulated lactoperoxidase (LP) or horseradishperoxidase (HRP) catalyzed iodination of tyrosine, the stimulation being more pronounced in case of LP.
Ray, Pradip K.   +2 more
core   +1 more source

Erythropoietin Production in the Kidney

open access: yes, 1987
The hormone erythropoietin stimulates erythrocyte production and therefore regulates the oxygen capacity of the blood. Hypoxia promotes erythropoietin formation by stimulating the transcription of the erythropoietin gene in the kidney and, to a lesser ...
A Kurtz, C Bauer
core   +1 more source

Daily hot‐water immersion preserves altitude‐induced haemoglobin mass expansion following descent independent of erythropoietin

open access: yesExperimental Physiology, EarlyView.
Abstract High‐altitude exposure increases haemoglobin mass (Hbmass), a key determinant of arterial oxygen‐carrying capacity, but following descent this adaptation can regress toward baseline within 7 days. Long‐term heat acclimation has emerged as an alternative stimulus for Hbmass expansion; however, whether post‐altitude passive‐heat exposure can ...
Elliott J. Jenkins   +12 more
wiley   +1 more source

Erythropoietin: current aspects and prospects

open access: yes, 1989
Authors have reviewed recent literature on erythropoietin. They report new information regarding synthesis, modulation, changes during several diseases and the possibility for a clinical use of erythropoietin for the correction of many anaemias.
CERUSO D.   +5 more
core  

Exercise intolerance and impaired aerobic capacity in heart transplant recipients

open access: yesExperimental Physiology, EarlyView.
Abstract Heart transplant recipients exhibit reduced exercise tolerance and persistently diminished aerobic capacity despite exercise training. Exercise tolerance depends on integrated oxygen transport and utilization, which are impaired in heart transplant recipients.
Fred W. Kolkhorst   +2 more
wiley   +1 more source

Physical activity partly inhibits autonomic imbalance, immune dysfunction and quality of life induced by chronic shiftwork in policemen

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic shiftwork can impair autonomic cardiovascular regulation and immune homeostasis. However, the interaction between occupational status and physical activity level in military police officers remains incompletely understood. This cross‐sectional factorial study included 102 men stratified according to occupational status and physical ...
Hélida C. Aquino‐Santos   +11 more
wiley   +1 more source

Exogenous ketosis in breath‐hold diving: Promise, paradox and physiological risk

open access: yesExperimental Physiology, EarlyView.
Abstract Exogenous ketosis induced by ketone ester (KE) ingestion has attracted growing interest as a potential strategy to enhance physiological tolerance to reduced O2 availability. Reported benefits arise largely from KE‐induced hyperventilation, which can improve systemic and tissue oxygenation during altitude exposure and hypoxic exercise ...
Ivan Drviš   +5 more
wiley   +1 more source

The ‘lactate paradox’ revisited after 35 years: In memoriam Paolo Cerretelli

open access: yesExperimental Physiology, EarlyView.
Abstract Some decades ago significant scientific interest was raised by the concept of the ‘lactate paradox’ occurring during altitude acclimatization. In short, in acute hypoxia blood lactate− concentration ([La]b) is higher, compared to normoxia, at any given submaximal work rate, whereas peak [La]b at exhausting exercise is unchanged.
Bruno Grassi
wiley   +1 more source

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