Testing for recombinant human erythropoietin [PDF]
, 2008 Delanghe, Joris, Joyner, Michael
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Emergence of the Biosimilar Sector and Opportunities of Developing Country Suppliers [PDF]
, 2011 As biologic products begin to come off-patent, a market is emerging for biosimilars (also known as biogenerics or follow-on biologics). Firms from emerging countries such as India and China have dominated the production of active ingredients in ...
Huzair, Farah, Kale, Dinar
core
Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface
Plant Biotechnology Journal, EarlyView.ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng +8 more
wiley +1 more source
Impact of Expanded Hemodialysis on Inflammation and Iron Metabolism in Chronic Hemodialysis Patients
Seminars in Dialysis, EarlyView.ABSTRACT Microinflammation and functional iron deficiency are major contributors to anemia and treatment burden in maintenance hemodialysis (HD). Medium cutoff (MCO) membranes enhance the removal of middle‐ and large‐sized solutes implicated in these pathways, yet real‐world data using routinely measured inflammatory and iron‐related markers are scarce.
Berrak Itır Aylı +2 more
wiley +1 more source
Comparison of early reactions of the blood system in rats to immobilization, the action of hypoxia and the administration of erythopoietin [PDF]
Three series of experiments were simultaneously carried on rats with the purpose of studying the action of different stimulants on the blood system; rats were subjected to immobilization, hypoxic hypoxia and erythropoietin administration.
Belousova, O. I. +3 more
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Hypoxia enhances the tissue protective effect of erythropoietin and its analogues in an endothelial cell injury model [PDF]
, 2015 PO has tissue protective activities in ischemic disease but also has prothrombotic, erythropoietic effects. Carbamylated EPO (CEPO) retains the protective actions without the erythropoietic effects.
Ferns, Gordon +3 more
core
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury.
Proceedings of the National Academy of Sciences of the United States of America, 2000 M. Brines +7 more
semanticscholar +1 more source
Codocytosis in the Dog: 345 Cases (2020–2022)
Veterinary Clinical Pathology, EarlyView.ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker +5 more
wiley +1 more source
The stages in standardizing erythropoietin preparations
Биопрепараты: Профилактика, диагностика, лечение, 2018 Preparations of recombinant human erythropoietin (rhEPO) are included in the list of vital and essential drugs for medical use. When evaluating the quality of EPO preparations during the manufacturing process, under the state marketing authorization and ...
A. K. Yakovlev +7 more
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