Haptoglobin genotypes, inflammation status and their associations with hemoglobin levels in stage 4 chronic kidney disease patients with anemia [PDF]
Background and aims: Anemia and increased inflammation are the main causes of mortality in chronic kidney disease (CKD) patients. This study was designed to explore the probable relationship of hemoglobin (Hb) with serum haptoglobin (HP), its ...
ارگانی, حسن +3 more
core
Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma
Veterinary Clinical Pathology, EarlyView.ABSTRACT A 7‐year‐old, male, castrated, mixed‐breed dog presented with right pelvic limb lameness and pain on posturing to defecate that began 1.5 years prior to presentation. Radiographs taken 8 months prior to presentation showed a small lytic lesion of the L6 vertebral body, and CBCs showed a persistently increased hematocrit (HCT) for at least 2 ...
Samuel V. Neal +11 more
wiley +1 more source
Dynamic regulation of erythropoiesis: A computer model of general applicability [PDF]
A mathematical model for the control of erythropoiesis was developed based on the balance between oxygen supply and demand at a renal oxygen detector which controls erythropoietin release and red cell production.
Leonard, J. I.
core +1 more source
Downregulation of EPAS1 and EGLN1 mRNA Expression Associated With High-Altitude Adaptive Genetic Variants in Sherpa Highlanders. [PDF]
Ann Hum GenetABSTRACT Background and Aims Sherpa highlanders exhibit remarkable tolerance to hypoxia, most likely due to genetic adaptations shaped by natural selection at high altitude. This study examined the roles of endothelial PAS domain protein 1 (EPAS1) and egl‐9 family hypoxia‐inducible factor 1 (EGLN1) in the genetic mechanisms underlying this adaptation ...
Droma Y +5 more
europepmc +2 more sources
Association of red blood cell transfusions with periventricular leukomalacia in very preterm infants
Vox Sanguinis, EarlyView.Abstract Background and Objectives Red blood cell (RBC) transfusions have been associated with retinopathy of prematurity (ROP) and adverse long‐term neurodevelopmental outcomes in very preterm infants. Although lower transfusion thresholds reduce the incidence of ROP, they have not improved neurological outcome. Periventricular leukomalacia (PVL) is a
Thomas Brune +2 more
wiley +1 more source
Parenteral iron—Does it increase infection risk?
Vox Sanguinis, EarlyView.Abstract Background and Objectives Iron deficiency (ID) and iron deficiency anaemia (IDA) are prevalent conditions impacting various patient populations, both surgical and non‐surgical conditions. The advent of patient blood management (PBM) has promoted intravenous (IV) iron therapy as an alternative to oral iron and blood transfusions.
Joyisa Deb +7 more
wiley +1 more source
Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice [PDF]
, 2017 Jin, Hongting +10 more
core +2 more sources
Use of a computer model in the understanding of erythropoietic control mechanisms [PDF]
During an eight-week visit approximately 200 simulations using the computer model for the regulation of erythopoiesis were carries out in four general areas: with the human model simulating hypoxia and dehydration, evaluation of the simulation of ...
Dunn, C. D. R.
core +1 more source