Results 171 to 180 of about 80,709 (284)

Impact of Anemia and Comorbidity Burden on Disease Progression and Outcomes in Chronic Kidney Disease

Journal of Clinical Laboratory Analysis, Volume 40, Issue 17, September 2026.
This study evaluates the prognostic value of immuno‐hematological markers—including anemia status, RDW, hemoglobin levels, and multimorbidity burden—in predicting chronic kidney disease (CKD) progression among adult patients. Findings reveal that anemia and the presence of ≥ 2 comorbidities strongly amplify the risk of CKD progression and ...
Collince Odiwuor Ogolla, Stanslaus Musyoki, Lucy W. Karani, Phidelis Maruti   +3 more
wiley   +1 more source

My Love Story With HIFs in the Disc: A Journey to the Humboldt Research Award

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT The intervertebral disc is a prime example of tissue adaptation to metabolic and mechanical extremes. As the largest avascular organ in the human body, the disc and the central nucleus pulposus (NP) endure constant compressive loading while sustaining a hypoxic, relatively acidic, and hyperosmotic microenvironment that would be inhospitable to
Makarand V. Risbud
wiley   +1 more source

Subacute-Onset Anemia Following COVID-19 Vaccine Combination with ChAdOx (AstraZeneca) and BNT162b2 (BioNTech, Pfizer)-A Case Report. [PDF]

Reports (MDPI)
Salveridou K, Tzamalis T, Haase S, Giagounidis A.   +3 more
europepmc   +1 more source

Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao, Jinxiu Qian, Qiqiong Liu, Wanting Ye, Ying Xing, Xiuyun Bai, Rongjun Deng, Jue Yang, Cheng Lu, Cheng Xiao, Yuanyan Liu   +10 more
wiley   +1 more source

[Corrigendum] Effect of SDF‑1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury. [PDF]

Int J Mol Med
Li J, Guo W, Xiong M, Han H, Chen J, Mao D, Tang B, Yu H, Zeng Y.   +8 more
europepmc   +1 more source

Bioinformatics Analysis and Experimental Validation of Key Genes Associated With Hypoxia and Ischemia in Myocardial Infarction

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study screened hypoxia‐ischemia hub genes for AMI through transcriptomic bioinformatics and animal tests. Merging two GEO datasets yielded 633 DEGs; intersection with GeneCards hypoxia genes produced 21 HIRGs. PPI network and random forest identified core PLAUR and IL1B, whose diagnostic value was validated by GSE66360 via ROC, calibration, and ...
Longsheng Zhang, Ning Liang
wiley   +1 more source

Anemia of Chronic Disease: Pathophysiology, Diagnosis and Management. [PDF]

Hematol Rep
Abbotts K, Sriskandarajah P.
europepmc   +1 more source

Phenotypic and Genotypic Landscape of Sitosterolemia in China: Including a Rare Case With Nephronophthisis

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study describes the first reported case of concurrent sitosterolemia (STSL) and nephronophthisis (NPHP). Additionally, we provide a systematic review of the clinical and genetic characteristics of Chinese STSL patients, representing the largest comprehensive cohort in China to date.
Dan Ding, Hongmei Wu, Fei Zhao, Bixia Zheng, Qiuxia Chen   +4 more
wiley   +1 more source

Association of Malnutrition, Inflammation, and Residual Kidney Clearance in Peritoneal Dialysis: A Cross-Sectional Analysis. [PDF]

Int J Nephrol
Jeerangsapasuk W, Wichitkul C, Boonkerd T, Wisettorn S, Chatkrailert A.   +4 more
europepmc   +1 more source

Mechanistic Insights Into Hepatotoxicity‐Induced Liver Cirrhosis and Anemia: Iron Dysregulation, the Hepcidin–Ferroportin Axis, and Emerging Therapeutic Strategies

Organ Medicine, Volume 3, Issue 3, Page 171-185, September 2026.
Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley   +1 more source